Literature DB >> 17924878

The use of recombinant human epidermal growth factor to promote healing for chronic radiation ulcer.

Sang-wook Lee1, Sue Young Moon, Yeun Hwa Kim, Joon Pio Hong.   

Abstract

This case report describes the first successful use of recombinant human epidermal growth factor (rh-EGF) in radiation-induced chronic wound of bone and skin which remains to be difficult to treat. Such wound on the chest of a 59-year-old female patient is presented lasting 3 years despite flap surgery and conventional treatment. The treatment with rh-EGF achieved healing within 16 weeks but further study to evaluate its potential for radiation-induced chronic wounds is warranted.

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Year:  2007        PMID： 17924878      PMCID： PMC7951463          DOI： 10.1111/j.1742-481X.2007.00332.x

Source DB:  PubMed          Journal:  Int Wound J        ISSN： 1742-4801            Impact factor:   3.315


  23 in total

1.  Intradermal injection of autologous dermal fibroblasts improves wound healing in irradiated skin.

Authors:  P C Ferguson; E L Boynton; J S Wunder; R P Hill; B O'Sullivan; J S Sandhu; R S Bell
Journal:  J Surg Res       Date:  1999-08       Impact factor: 2.192

Review 2.  Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts.

Authors:  M Hetzel; M Bachem; D Anders; G Trischler; M Faehling
Journal:  Lung       Date:  2005 Jul-Aug       Impact factor: 2.584

3.  The effect of graft-bed irradiation on the healing of rat skin grafts.

Authors:  Q Wang; G R Dickson; K E Carr
Journal:  J Invest Dermatol       Date:  1996-05       Impact factor: 8.551

4.  Molecular targeting in radiotherapy: epidermal growth factor receptor.

Authors:  Theodore D Chung; William C Broaddus
Journal:  Mol Interv       Date:  2005-02

5.  Increased expression of the epidermal growth factor receptor in human epidermal keratinocytes after exposure to ionizing radiation.

Authors:  R U Peter; A Beetz; C Ried; G Michel; D van Beuningen; T Ruzicka
Journal:  Radiat Res       Date:  1993-10       Impact factor: 2.841

6.  Differential regulation of the expression of transforming growth factor-beta s 1 and 2 by retinoic acid, epidermal growth factor, and dexamethasone in NRK-49F and A549 cells.

Authors:  D Danielpour; K Y Kim; T S Winokur; M B Sporn
Journal:  J Cell Physiol       Date:  1991-08       Impact factor: 6.384

7.  Kinetics of epidermal growth factor in saliva.

Authors:  M Ino; K Ushiro; C Ino; T Yamashita; T Kumazawa
Journal:  Acta Otolaryngol Suppl       Date:  1993

8.  Slowed growth of cultured fibroblasts from human radiation wounds.

Authors:  R Rudolph; J Vande Berg; J A Schneider; J C Fisher; W L Poolman
Journal:  Plast Reconstr Surg       Date:  1988-10       Impact factor: 4.730

9.  Normal transcutaneous oxygen pressure in skin after radiation therapy for cancer.

Authors:  R Rudolph; P Tripuraneni; J A Koziol; M McKean-Matthews; A Frutos
Journal:  Cancer       Date:  1994-12-01       Impact factor: 6.860

Review 10.  The radiotherapeutic injury--a complex 'wound'.

Authors:  James W Denham; Martin Hauer-Jensen
Journal:  Radiother Oncol       Date:  2002-05       Impact factor: 6.280
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  3 in total

1.  Epidermal growth factor or platelet-rich plasma combined with induced membrane technique in the treatment of segmental femur defects: an experimental study.

Authors:  Ökkeş Bilal; Duran Topak; Mustafa Kınaş; Ergül Belge Kurutaş; Betül Kızıldağ; Abdulkadir Yasir Bahar
Journal:  J Orthop Surg Res       Date:  2020-12-11       Impact factor: 2.359

2.  Foam dressing with epidermal growth factor for severe radiation dermatitis in head and neck cancer patients.

Authors:  Jihyo Lee; Sang-Wook Lee; Joon Pio Hong; Myeong Wha Shon; Seung-Hee Ryu; Seung Do Ahn
Journal:  Int Wound J       Date:  2014-06-20       Impact factor: 3.315

3.  Paradoxical induction of growth arrest and apoptosis by EGF via the up-regulation of PTEN by activating Redox factor-1/Egr-1 in human lung cancer cells.

Authors:  Je-Won Ryu; Sung Sik Choe; Seung-Hee Ryu; Eun-Young Park; Byoung Wook Lee; Tae Keun Kim; Chang Hoon Ha; Sang-Wook Lee
Journal:  Oncotarget       Date:  2017-01-17
  3 in total

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