Literature DB >> 17923081

How to assemble a capsid.

Wesley I Sundquist1, Christopher P Hill.   

Abstract

Retroviral capsids are composed of hexagonal arrays of the viral CA protein. In this issue of Cell, Ganser-Pornillos et al. (2007) provide a molecular model of the hexagonal HIV-1 CA lattice obtained from a new electron cryomicroscopic reconstruction. This study reveals the three principal stabilizing interfaces in the capsid lattice and explains how two different classes of inhibitors can block capsid assembly.

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Year:  2007        PMID： 17923081     DOI： 10.1016/j.cell.2007.09.028

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  14 in total

1.  Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid.

Authors:  Shibani Bhattacharya; Hongtao Zhang; Asim K Debnath; David Cowburn
Journal:  J Biol Chem       Date:  2008-04-16       Impact factor: 5.157

2.  Distinct effects of two HIV-1 capsid assembly inhibitor families that bind the same site within the N-terminal domain of the viral CA protein.

Authors:  Christopher T Lemke; Steve Titolo; Uta von Schwedler; Nathalie Goudreau; Jean-François Mercier; Elizabeth Wardrop; Anne-Marie Faucher; René Coulombe; Soma S R Banik; Lee Fader; Alexandre Gagnon; Stephen H Kawai; Jean Rancourt; Martin Tremblay; Christiane Yoakim; Bruno Simoneau; Jacques Archambault; Wesley I Sundquist; Stephen W Mason
Journal:  J Virol       Date:  2012-04-11       Impact factor: 5.103

3.  Structure of a monomeric mutant of the HIV-1 capsid protein.

Authors:  Ronald Shin; Ywh-Min Tzou; N Rama Krishna
Journal:  Biochemistry       Date:  2011-10-13       Impact factor: 3.162

4.  Two-hybrid analysis of Ty3 capsid subdomain interactions.

Authors:  Min Zhang; Liza Sz Larsen; Becky Irwin; Virginia Bilanchone; Suzanne Sandmeyer
Journal:  Mob DNA       Date:  2010-05-05

5.  Unclosed HIV-1 capsids suggest a curled sheet model of assembly.

Authors:  Zhiheng Yu; Megan J Dobro; Cora L Woodward; Artem Levandovsky; Cindy M Danielson; Virginie Sandrin; Jiong Shi; Christopher Aiken; Roya Zandi; Thomas J Hope; Grant J Jensen
Journal:  J Mol Biol       Date:  2012-10-16       Impact factor: 5.469

6.  A single amino acid substitution in a segment of the CA protein within Gag that has similarity to human immunodeficiency virus type 1 blocks infectivity of a human endogenous retrovirus K provirus in the human genome.

Authors:  David J Heslin; Pablo Murcia; Frederick Arnaud; Koenraad Van Doorslaer; Massimo Palmarini; Jack Lenz
Journal:  J Virol       Date:  2008-11-12       Impact factor: 5.103

7.  A structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins.

Authors:  Natsuko Inagaki; Hiroaki Takeuchi; Masaru Yokoyama; Hironori Sato; Akihide Ryo; Hiroyuki Yamamoto; Miki Kawada; Tetsuro Matano
Journal:  Retrovirology       Date:  2010-10-18       Impact factor: 4.602

8.  High-throughput profiling of point mutations across the HIV-1 genome.

Authors:  Laith Q Al-Mawsawi; Nicholas C Wu; C Anders Olson; Vivian Cai Shi; Hangfei Qi; Xiaojuan Zheng; Ting-Ting Wu; Ren Sun
Journal:  Retrovirology       Date:  2014-12-19       Impact factor: 4.602

9.  Mutational analysis and allosteric effects in the HIV-1 capsid protein carboxyl-terminal dimerization domain.

Authors:  Xiang Yu; Qiuming Wang; Jui-Chen Yang; Idit Buch; Chung-Jung Tsai; Buyong Ma; Stephen Z D Cheng; Ruth Nussinov; Jie Zheng
Journal:  Biomacromolecules       Date:  2009-02-09       Impact factor: 6.988

10.  Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

Authors:  Anastasia Selyutina; Mirjana Persaud; Lacy M Simons; Angel Bulnes-Ramos; Cindy Buffone; Alicia Martinez-Lopez; Viviana Scoca; Francesca Di Nunzio; Joseph Hiatt; Alexander Marson; Nevan J Krogan; Judd F Hultquist; Felipe Diaz-Griffero
Journal:  Cell Rep       Date:  2020-03-17       Impact factor: 9.423
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