Literature DB >> 17923080

Loss of T-bet sends host-microbe mutualism awry.

Averil Ma1.   

Abstract

Immune homeostasis in the intestine involves complex interactions between microbial organisms and host cells. In this issue, Garrett et al. (2007) describe a communicable form of colitis that is induced by deficiency of the transcription factor T-bet in cells of the innate immune system.

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Year:  2007        PMID: 17923080     DOI: 10.1016/j.cell.2007.09.030

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  2 in total

Review 1.  Interplay between DNA repair and inflammation, and the link to cancer.

Authors:  Dawit Kidane; Wook Jin Chae; Jennifer Czochor; Kristin A Eckert; Peter M Glazer; Alfred L M Bothwell; Joann B Sweasy
Journal:  Crit Rev Biochem Mol Biol       Date:  2014-01-13       Impact factor: 8.250

2.  Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells.

Authors:  Wendy S Garrett; Shivesh Punit; Carey A Gallini; Monia Michaud; Dorothy Zhang; Kirsten S Sigrist; Graham M Lord; Jonathan N Glickman; Laurie H Glimcher
Journal:  Cancer Cell       Date:  2009-09-08       Impact factor: 31.743

  2 in total

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