Literature DB >> 1792224

Transferrin is a growth factor for the bloodstream form of Trypanosoma brucei.

D Schell1, N K Borowy, P Overath.   

Abstract

A method for the selective depletion of transferrin from bovine serum is presented. Bloodstream forms of Trypanosoma brucei cannot grow in medium containing transferrin-deficient serum, whereas reconstitution with transferrin restores normal growth. We conclude that transferrin is an essential growth factor for the mammalian stage of the parasite.

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Year:  1991        PMID： 1792224     DOI： 10.1007/bf00931012

Source DB:  PubMed          Journal:  Parasitol Res        ISSN： 0932-0113            Impact factor:   2.289


  13 in total

1.  Characterization of a cDNA encoding a cysteine-rich cell surface protein located in the flagellar pocket of the protozoan Trypanosoma brucei.

Authors:  M G Lee; B E Bihain; D G Russell; R J Deckelbaum; L H Van der Ploeg
Journal:  Mol Cell Biol       Date:  1990-09       Impact factor: 4.272

2.  Receptor-mediated endocytosis in the bloodstream form of Trypanosoma brucei.

Authors:  I Coppens; F R Opperdoes; P J Courtoy; P Baudhuin
Journal:  J Protozool       Date:  1987-11

3.  Receptors for the host low density lipoproteins on the hemoflagellate Trypanosoma brucei: purification and involvement in the growth of the parasite.

Authors:  I Coppens; P Baudhuin; F R Opperdoes; P J Courtoy
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

Review 4.  Cultivation of African and South American trypanosomes of medical or veterinary importance.

Authors:  R Brun; L Jenni
Journal:  Br Med Bull       Date:  1985-04       Impact factor: 4.291

5.  Serum lipoprotein and Trypanosoma brucei brucei interactions in vitro.

Authors:  V Vandeweerd; S J Black
Journal:  Mol Biochem Parasitol       Date:  1989-12       Impact factor: 1.759

6.  Phylogenetical and ontogenetical studies on the molecular weight heterogeneity of bovine serum transferrin.

Authors:  S Tsuji; H Kato; Y Matsuoka; T Fukushima; I Nanjoh; T Amano; T Namikawa
Journal:  Biochem Genet       Date:  1984-12       Impact factor: 1.890

7.  Identification of an epidermal growth factor receptor homologue in trypanosomes.

Authors:  G Hide; A Gray; C M Harrison; A Tait
Journal:  Mol Biochem Parasitol       Date:  1989-08       Impact factor: 1.759

8.  Molecular weight heterogeneity of bovine serum transferrin.

Authors:  S Tsuji; H Kato; Y Matsuoka; T Fukushima
Journal:  Biochem Genet       Date:  1984-12       Impact factor: 1.890

9.  Intracellular colocalization of variant surface glycoprotein and transferrin-gold in Trypanosoma brucei.

Authors:  P Webster; D J Grab
Journal:  J Cell Biol       Date:  1988-02       Impact factor: 10.539

10.  A transferrin-binding protein of Trypanosoma brucei is encoded by one of the genes in the variant surface glycoprotein gene expression site.

Authors:  D Schell; R Evers; D Preis; K Ziegelbauer; H Kiefer; F Lottspeich; A W Cornelissen; P Overath
Journal:  EMBO J       Date:  1991-05       Impact factor: 11.598
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  18 in total

1.  Immunobiology of African trypanosomes: need of alternative interventions.

Authors:  Toya Nath Baral
Journal:  J Biomed Biotechnol       Date:  2010-02-23

Review 2.  Protein trafficking in kinetoplastid protozoa.

Authors:  C Clayton; T Häusler; J Blattner
Journal:  Microbiol Rev       Date:  1995-09

3.  Expression of a glycosylphosphatidylinositol-anchored Trypanosoma brucei transferrin-binding protein complex in insect cells.

Authors:  M Chaudhri; D Steverding; D Kittelberger; S Tjia; P Overath
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-05       Impact factor: 11.205

4.  AEE788 Inhibits Basal Body Assembly and Blocks DNA Replication in the African Trypanosome.

Authors:  Catherine Sullenberger; Daniel Piqué; Yuko Ogata; Kojo Mensa-Wilmot
Journal:  Mol Pharmacol       Date:  2017-02-28       Impact factor: 4.436

5.  Iron-dependent regulation of transferrin receptor expression in Trypanosoma brucei.

Authors:  B Fast; K Kremp; M Boshart; D Steverding
Journal:  Biochem J       Date:  1999-09-15       Impact factor: 3.857

6.  Glycogen Synthase Kinase 3β Promotes the Endocytosis of Transferrin in the African Trypanosome.

Authors:  Paul J Guyett; Shuangluo Xia; David C Swinney; Michael P Pollastri; Kojo Mensa-Wilmot
Journal:  ACS Infect Dis       Date:  2016-06-16       Impact factor: 5.084

7.  Glutathione and iron at the crossroad of redox metabolism in rats infected by Trypanosoma evansi.

Authors:  Valesca Anschau; Alcir Luiz Dafré; Ana Paula Perin; Fabíola Iagher; Mayara Vieira Tizatto; Luiz Claudio Miletti
Journal:  Parasitol Res       Date:  2013-03-26       Impact factor: 2.289

8.  Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation.

Authors:  Jennifer L Woodring; Ranjan Behera; Amrita Sharma; Justin Wiedeman; Gautam Patel; Baljinder Singh; Paul Guyett; Emanuele Amata; Jessey Erath; Norma Roncal; Erica Penn; Susan E Leed; Ana Rodriguez; Richard J Sciotti; Kojo Mensa-Wilmot; Michael P Pollastri
Journal:  ACS Med Chem Lett       Date:  2018-09-04       Impact factor: 4.345

9.  The trypanosome Rab-related proteins RabX1 and RabX2 play no role in intracellular trafficking but may be involved in fly infectivity.

Authors:  Senthil Kumar A Natesan; Lori Peacock; Ka Fai Leung; Keith R Matthews; Wendy Gibson; Mark C Field
Journal:  PLoS One       Date:  2009-09-29       Impact factor: 3.240

10.  Diacylglycerol-stimulated endocytosis of transferrin in trypanosomatids is dependent on tyrosine kinase activity.

Authors:  Sandesh Subramanya; Kojo Mensa-Wilmot
Journal:  PLoS One       Date:  2010-01-01       Impact factor: 3.240
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