| Literature DB >> 17922113 |
Daisaku Ohta1, Daisuke Shibata, Shigehiko Kanaya.
Abstract
With the aid of the extreme resolving power of Fourier-transform ion-cyclotron-resonance mass spectrometry (FT-ICR/MS), we have developed a metabolomics platform for high-throughput metabolic profiling and metabolite candidate identification integrating a data-processing system, the Dr.DMASS program ( http://kanaya.naist.jp/DrDMASS/ ), and a metabolite-species database, KNApSAcK ( http://kanaya.aist-nara.ac.jp/KNApSAcK/ ). We discuss the potential of this FT-ICR/MS-based metabolic profiling scheme as a general metabolomics tool by clarification of plant metabolic disorders and specific metabolite accumulation patterns caused by herbicidal enzyme inhibitors.Entities:
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Year: 2007 PMID: 17922113 DOI: 10.1007/s00216-007-1650-z
Source DB: PubMed Journal: Anal Bioanal Chem ISSN: 1618-2642 Impact factor: 4.142