Literature DB >> 17921765

Clinical challenges in the treatment of patients with posttraumatic stress disorder and substance abuse.

Ingo Schäfer1, Lisa M Najavits.   

Abstract

PURPOSE OF REVIEW: The aim of this article is to review the current literature on co-occuring posttraumatic stress disorder and substance-use disorder, with an emphasis on clinical aspects and emerging treatments. RECENT
FINDINGS: In clinical populations (focusing on either disorder), about 25-50% have a lifetime dual diagnosis of posttraumatic stress disorder and substance-use disorder. Patients with both disorders have a more severe clinical profile than those with either disorder alone, lower functioning, poorer well being, and worse outcomes across a variety of measures. In recent years, several promising treatment programs have been developed specifically for co-occuring posttraumatic stress disorder and substance-use disorder, with one model having been established as effective thus far.
SUMMARY: Comorbid posttraumatic stress disorder/substance-use disorder is a frequent diagnosis in clinical populations that severely affects course and outcome. Treatment approaches appropriate for this vulnerable population need to be evaluated further and implemented in routine practice.

Entities:  

Mesh:

Year:  2007        PMID: 17921765     DOI: 10.1097/YCO.0b013e3282f0ffd9

Source DB:  PubMed          Journal:  Curr Opin Psychiatry        ISSN: 0951-7367            Impact factor:   4.741


  39 in total

1.  When the medial prefrontal cortex fails: implications for extinction and posttraumatic stress disorder treatment.

Authors:  Peter A Groblewski; James M Stafford
Journal:  J Neurosci       Date:  2010-05-26       Impact factor: 6.167

2.  Relations Between Cognitive Functioning and Alcohol Use, Craving, and Post-Traumatic Stress: An Examination Among Trauma-Exposed Military Veterans With Alcohol Use Disorder.

Authors:  Adrienne J Heinz; David L Pennington; Nicole Cohen; Brandi Schmeling; Brooke A Lasher; Emily Schrodek; Steven L Batki
Journal:  Mil Med       Date:  2016-07       Impact factor: 1.437

Review 3.  Substance use modulates stress reactivity: Behavioral and physiological outcomes.

Authors:  Anne Q Fosnocht; Lisa A Briand
Journal:  Physiol Behav       Date:  2016-02-19

4.  Mindfulness as a predictor of cognitive-behavioral therapy outcomes in inner-city adults with posttraumatic stress and substance dependence.

Authors:  Anka A Vujanovic; Lia J Smith; Charles Green; Scott D Lane; Joy M Schmitz
Journal:  Addict Behav       Date:  2019-12-30       Impact factor: 3.913

Review 5.  Treatment of substance abusing patients with comorbid psychiatric disorders.

Authors:  Thomas M Kelly; Dennis C Daley; Antoine B Douaihy
Journal:  Addict Behav       Date:  2011-09-14       Impact factor: 3.913

6.  Demographic and clinical characteristics of treatment seeking women with full and subthreshold PTSD and concurrent cannabis and cocaine use disorders.

Authors:  Lesia M Ruglass; Alina Shevorykin; Christina Brezing; Mei-Chen Hu; Denise A Hien
Journal:  J Subst Abuse Treat       Date:  2017-06-28

Review 7.  Neurobiology of comorbid post-traumatic stress disorder and alcohol-use disorder.

Authors:  N W Gilpin; J L Weiner
Journal:  Genes Brain Behav       Date:  2016-11-18       Impact factor: 3.449

8.  Negative affect and emotion dysregulation among people who inject drugs: An ecological momentary assessment study.

Authors:  Mary Ellen Mackesy-Amiti; Geri Donenberg
Journal:  Psychol Addict Behav       Date:  2020-04-09

9.  Impact of Family History in Persons With Dual Diagnosis.

Authors:  Camille S Wilson; Melanie E Bennett; Alan S Bellack
Journal:  J Dual Diagn       Date:  2012-11-27

10.  Assessment of plasma C-reactive protein as a biomarker of posttraumatic stress disorder risk.

Authors:  Satish A Eraly; Caroline M Nievergelt; Adam X Maihofer; Donald A Barkauskas; Nilima Biswas; Agorastos Agorastos; Daniel T O'Connor; Dewleen G Baker
Journal:  JAMA Psychiatry       Date:  2014-04       Impact factor: 21.596

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