Literature DB >> 17920984

Ketamine for prehospital use: new look at an old drug.

James E Svenson1, Michael K Abernathy.   

Abstract

INTRODUCTION: Ketamine has been used extensively for analgesia and anesthesia in many situations, including disaster surgery where extra personnel and advanced monitoring are not available. There are many features of ketamine that seem to make it an ideal drug for prehospital use. The reported use of ketamine in the prehospital environment is limited, however. The purpose of this study is to review the experience in the use of ketamine in a regional air ambulance service and suggest indications for its use in the prehospital setting.
METHODS: This was a retrospective study of all patients transported by a regional aeromedical program. Patients were included in this study if the crew had used ketamine at any time during the flight. Data regarding the transport collected included patient age, type of transport, indications for ketamine use, and adverse reactions.
RESULTS: During the period studied, ketamine was used in 40 patients. The age range was 2 months to 75 years. The indications and situations requiring use were varied and included both trauma and medical patients. Hypotension with need for analgesia, agitation or combativeness and intact airway, or pain unresponsive to narcotic medications were the most common indications for use. Ketamine was used both intravenous and intramuscular, even without intravenous access. There were no adverse reactions.
CONCLUSIONS: Ketamine is an ideal drug for use in many prehospital situations. Our experience suggests that it is safe, effective, and may be more appropriate than drugs currently used by prehospital providers.

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Year:  2007        PMID: 17920984     DOI: 10.1016/j.ajem.2007.02.040

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  18 in total

1.  Paradoxical Emergence: Administration of Subanesthetic Ketamine during Isoflurane Anesthesia Induces Burst Suppression but Accelerates Recovery.

Authors:  Viviane S Hambrecht-Wiedbusch; Duan Li; George A Mashour
Journal:  Anesthesiology       Date:  2017-03       Impact factor: 7.892

Review 2.  Treating pain on the battlefield: a warrior's perspective.

Authors:  Chester C Buckenmaier; Hisani Brandon-Edwards; David Borden; John Wright
Journal:  Curr Pain Headache Rep       Date:  2010-02

Review 3.  The Evolving Landscape of Acute Pain Management in the Era of the Opioid Crisis.

Authors:  Ali Pourmand; Gregory Jasani; Courtney Shay; Maryann Mazer-Amirshahi
Journal:  Curr Pain Headache Rep       Date:  2018-08-27

Review 4.  Ketamine in pain management.

Authors:  Jan Persson
Journal:  CNS Neurosci Ther       Date:  2013-05-11       Impact factor: 5.243

5.  The analgesic effect of combined treatment with intranasal S-ketamine and intranasal midazolam compared with morphine patient-controlled analgesia in spinal surgery patients: a pilot study.

Authors:  Christine Riediger; Manuel Haschke; Christoph Bitter; Thomas Fabbro; Stefan Schaeren; Albert Urwyler; Wilhelm Ruppen
Journal:  J Pain Res       Date:  2015-02-13       Impact factor: 3.133

6.  Intranasal ketamine for acute traumatic pain in the Emergency Department: a prospective, randomized clinical trial of efficacy and safety.

Authors:  Shachar Shimonovich; Roy Gigi; Amir Shapira; Tal Sarig-Meth; Danielle Nadav; Mattan Rozenek; Debra West; Pinchas Halpern
Journal:  BMC Emerg Med       Date:  2016-11-09

Review 7.  Anesthesia Provision in Disasters and Armed Conflicts.

Authors:  Miguel Trelles Centurion; Rafael Van Den Bergh; Henry Gray
Journal:  Curr Anesthesiol Rep       Date:  2017-02-16

8.  Prehospital use of i.m. ketamine for sedation of violent and agitated patients.

Authors:  Kenneth A Scheppke; Joao Braghiroli; Mostafa Shalaby; Robert Chait
Journal:  West J Emerg Med       Date:  2014-11-11

9.  Ketamine for prehospital trauma analgesia in a low-resource rural trauma system: a retrospective comparative study of ketamine and opioid analgesia in a ten-year cohort in Iraq.

Authors:  Ole Kristian Losvik; Mudhafar Kareem Murad; Eystein Skjerve; Hans Husum
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2015-11-09       Impact factor: 2.953

Review 10.  Role of ketamine for analgesia in adults and children.

Authors:  Nalini Vadivelu; Erika Schermer; Vijay Kodumudi; Kumar Belani; Richard D Urman; Alan David Kaye
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2016 Jul-Sep
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