Literature DB >> 17920858

Epigenetics of antigen-receptor gene assembly.

Cornelis Murre1.   

Abstract

The antigen receptor genes are organized into distinct DNA elements that encode the variable (V), diversity (D) and joining (J) regions. It is now well established that the rearrangement of antigen receptor genes is regulated by developmental-specific modulation of chromatin structure. Further studies involving statistical mechanics should provide physical insight into the physical mechanisms that underlie the association of antigen receptor gene segments.

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Year:  2007        PMID： 17920858      PMCID： PMC2151926          DOI： 10.1016/j.gde.2007.08.006

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  49 in total

Review 1.  Chromatin dynamics and locus accessibility in the immune system.

Authors:  Raul Mostoslavsky; Frederick W Alt; Craig H Bassing
Journal:  Nat Immunol       Date:  2003-07       Impact factor: 25.606

Review 2.  Selection of the T-cell repertoire: receptor-controlled checkpoints in T-cell development.

Authors:  Harald von Boehmer
Journal:  Adv Immunol       Date:  2004       Impact factor: 3.543

3.  Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes to the allelic exclusion of light-chain expression.

Authors:  Hong-Erh Liang; Lih-Yun Hsu; Dragana Cado; Mark S Schlissel
Journal:  Cell       Date:  2004-07-09       Impact factor: 41.582

4.  B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5.

Authors:  Kristen Johnson; David L Pflugh; Duonan Yu; David G T Hesslein; Kuo-I Lin; Alfred L M Bothwell; Andrei Thomas-Tikhonenko; David G Schatz; Kathryn Calame
Journal:  Nat Immunol       Date:  2004-07-18       Impact factor: 25.606

Review 5.  Transcriptional control of early B cell development.

Authors:  Meinrad Busslinger
Journal:  Annu Rev Immunol       Date:  2004       Impact factor: 28.527

6.  Antisense intergenic transcription in V(D)J recombination.

Authors:  Daniel J Bolland; Andrew L Wood; Colette M Johnston; Sam F Bunting; Geoff Morgan; Lyubomira Chakalova; Peter J Fraser; Anne E Corcoran
Journal:  Nat Immunol       Date:  2004-04-25       Impact factor: 25.606

7.  E2A proteins enforce a proliferation checkpoint in developing thymocytes.

Authors:  Isaac Engel; Cornelis Murre
Journal:  EMBO J       Date:  2003-12-11       Impact factor: 11.598

8.  Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors.

Authors:  Sonja Höflinger; Kamala Kesavan; Martin Fuxa; Caroline Hutter; Barry Heavey; Freddy Radtke; Meinrad Busslinger
Journal:  J Immunol       Date:  2004-09-15       Impact factor: 5.422

9.  Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene.

Authors:  Martin Fuxa; Jane Skok; Abdallah Souabni; Giorgia Salvagiotto; Esther Roldan; Meinrad Busslinger
Journal:  Genes Dev       Date:  2004-02-15       Impact factor: 11.361

10.  Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A.

Authors:  Melanie W Quong; Annica Martensson; Anton W Langerak; Richard R Rivera; David Nemazee; Cornelis Murre
Journal:  J Exp Med       Date:  2004-04-12       Impact factor: 14.307
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  3 in total

1.  Constant domain-regulated antibody catalysis.

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Journal:  J Biol Chem       Date:  2012-09-04       Impact factor: 5.157

2.  T-cell receptor Vβ repertoire of CD8+ T-lymphocyte subpopulations in cutaneous leishmaniasis patients from the state of Rio de Janeiro, Brazil.

Authors:  Raquel Ferraz; Clarissa Ferreira Cunha; Maria Inês Pimentel; Marcelo Rosandiski Lyra; Armando Oliveira Schubach; Sérgio Coutinho Furtado de Mendonça; Alda Maria Da-Cruz; Alvaro Luiz Bertho
Journal:  Mem Inst Oswaldo Cruz       Date:  2015-06-24       Impact factor: 2.743

3.  Genetic variation stimulated by epigenetic modification.

Authors:  W Jason Cummings; David W Bednarski; Nancy Maizels
Journal:  PLoS One       Date:  2008-12-30       Impact factor: 3.240
  3 in total

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