| Literature DB >> 17920317 |
Simon Poulding1, Adrian J Charlton, James Donarski, Julie C Wilson.
Abstract
The presence of t(1) noise artefacts in 2D phase-cycled Heteronuclear Single Quantum Coherence (HSQC) spectra constrains the use of this experiment despite its superior sensitivity. This paper proposes a new processing algorithm, working in the frequency-domain, for reducing t(1) noise. The algorithm has been developed for use in contexts, such as metabolomic studies, where existing denoising techniques cannot always be applied. Two test cases are presented that show the algorithm to be effective in improving the SNR of peaks embedded within t(1) noise by a factor of more than 2, while retaining the intensity and shape of genuine peaks.Mesh：
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Year: 2007 PMID： 17920317 DOI： 10.1016/j.jmr.2007.09.004
Source DB: PubMed Journal: J Magn Reson ISSN： 1090-7807 Impact factor: 2.229