OBJECTIVE: To test the effects of father's alcoholism on the development and remission from alcoholic drinking by age 40. METHOD: Subjects were selected from a Danish birth cohort that included 223 sons of alcoholic fathers (high risk; HR) and 106 matched controls (low risk; LR). Clinical examinations were performed at age 40 (n = 202) by a psychiatrist using structured interviews and DSM-III-R diagnostic criteria. RESULTS: HR subjects were significantly more likely than LR subjects to develop alcohol dependence (31% vs. 16%), but not alcohol abuse (17% vs. 15%). More subjects with alcohol abuse were in remission at age 40 than subjects with alcohol dependence. Risk did not predict remission from either alcohol abuse or alcohol dependence. CONCLUSION: Familial influences may play a stronger role in the development of alcoholism than in the remission or recovery from alcoholism.
OBJECTIVE: To test the effects of father's alcoholism on the development and remission from alcoholic drinking by age 40. METHOD: Subjects were selected from a Danish birth cohort that included 223 sons of alcoholic fathers (high risk; HR) and 106 matched controls (low risk; LR). Clinical examinations were performed at age 40 (n = 202) by a psychiatrist using structured interviews and DSM-III-R diagnostic criteria. RESULTS: HR subjects were significantly more likely than LR subjects to develop alcohol dependence (31% vs. 16%), but not alcohol abuse (17% vs. 15%). More subjects with alcohol abuse were in remission at age 40 than subjects with alcohol dependence. Risk did not predict remission from either alcohol abuse or alcohol dependence. CONCLUSION: Familial influences may play a stronger role in the development of alcoholism than in the remission or recovery from alcoholism.
Authors: V V McCutcheon; J D Grant; A C Heath; K K Bucholz; C E Sartor; E C Nelson; P A F Madden; N G Martin Journal: Psychol Med Date: 2012-03-16 Impact factor: 7.723
Authors: Elizabeth C Penick; Joachim Knop; Elizabeth J Nickel; Per Jensen; Ann M Manzardo; Erik Lykke-Mortensen; William F Gabrielli Journal: J Stud Alcohol Drugs Date: 2010-09 Impact factor: 2.582
Authors: Vivia V McCutcheon; Marc A Schuckit; John R Kramer; Grace Chan; Howard J Edenberg; Tom L Smith; Annah K Bender; Victor Hesselbrock; Michie Hesselbrock; Kathleen K Bucholz Journal: Addiction Date: 2017-07-06 Impact factor: 6.526
Authors: Joachim Knop; Elizabeth C Penick; Elizabeth J Nickel; Erik L Mortensen; Margaret A Sullivan; Syed Murtaza; Per Jensen; Ann M Manzardo; William F Gabrielli Journal: J Stud Alcohol Drugs Date: 2009-03 Impact factor: 2.582