| Literature DB >> 17919002 |
Katarina Sapeta1, Michael A Kerr.
Abstract
The cycloaddition of nitrones and enantiomerically pure cyclopropane-1,1-dicarboxylates is examined. Transfer of optical activity to the adduct is dictated by thermal reaction conditions and nature of cyclopropane substitution. Optically active 2-substituted cyclopropane-1,1-dicarboxylates are shown to racemize under typical reaction conditions, providing evidence for a zwitterionic ring-opened intermediate.Entities:
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Year: 2007 PMID： 17919002 DOI： 10.1021/jo701606u
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354