Literature DB >> 17919

Stimulation of in vitro translation of messenger RNA by actinomycin D and cordycepin.

L Leinwand, F H Ruddle.   

Abstract

Actinomycin D and cordycepin were tested for their effect on translation in the wheat germ embryo extract and reticulocyte lysate assays for in vitro protein synthesis. Both drugs were found to stimulate the incorporation of 35S-labeled methionine into protein up to threefold as compared to control assays. This was true for synthesis directed by murine myeloma polyadenylate-containing RNA, tobacco mosaic virus RNA, and endogenous reticulocyte messenger RNA.

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Year:  1977        PMID： 17919     DOI： 10.1126/science.17919

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  8 in total

1.  Physical change in cytoplasmic messenger ribonucleoproteins in cells treated with inhibitors of mRNA transcription.

Authors:  G Dreyfuss; S A Adam; Y D Choi
Journal:  Mol Cell Biol       Date:  1984-03       Impact factor: 4.272

2.  Heating RNA before cell-free translation is essential for the efficient and reproducible synthesis of several peroxisomal proteins.

Authors:  R M Mortensen; R A Rachubinski; Y Fujiki; P B Lazarow
Journal:  Biochem J       Date:  1984-10-15       Impact factor: 3.857

3.  Protein-synthesizing activity of maize-shoot chromatin : I. Conditions and component requirements.

Authors:  B Wielgat; K Kleczkowski
Journal:  Plant Physiol       Date:  1986-06       Impact factor: 8.340

4.  Inhibition of ribonucleic acid efflux from isolated SV40-3T3 cell nuclei by 3'-deoxyadenosine (cordycepin).

Authors:  P S Agutter; B McCaldin
Journal:  Biochem J       Date:  1979-05-15       Impact factor: 3.857

5.  Role of calcium in the regulation of acetylcholine receptor synthese in cultured muscle cells*.

Authors:  M Birnbaum; M A Reis; A Shainberg
Journal:  Pflugers Arch       Date:  1980-05       Impact factor: 3.657

6.  The coupling of transcription from influenza virions to translation in vitro.

Authors:  P D Minor; N J Dimmock
Journal:  Arch Virol       Date:  1979       Impact factor: 2.574

7.  Superinduction of alpha 2u globulin by actinomycin D: evidence for drug-mediated increase in alpha 2u mRNA.

Authors:  B Chatterjee; J Hopkins; D Dutchak; A K Roy
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

8.  Induction of a biopolyester hydrolase (cutinase) by low levels of cutin monomers in Fusarium solani f.sp. pisi.

Authors:  T S Lin; P E Kolattukudy
Journal:  J Bacteriol       Date:  1978-02       Impact factor: 3.490
  8 in total

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