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Literature DB >> 1791897

Development of animal models of aging at the National Institute of Aging.

Abstract

The suitability of various animal species as experimental models of aging has been a continuing concern of the National Institute on Aging (NIA) for over 20 years. The history of the decisions made by NIA in providing aged animals for research may be helpful to individual investigators seeking to understand why certain models are available and which of them to choose for their work.

Mesh：

Year: 1991 PMID： 1791897 DOI： 10.1016/0197-4580(91)90113-x

Source DB: PubMed Journal: Neurobiol Aging ISSN： 0197-4580 Impact factor: 4.673

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Cited

19 in total

1. A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA.

Authors: M L Hamilton; Z Guo; C D Fuller; H Van Remmen; W F Ward; S N Austad; D A Troyer; I Thompson; A Richardson
Journal: Nucleic Acids Res Date: 2001-05-15 Impact factor: 16.971

Review 2. Innervation of the gastrointestinal tract: patterns of aging.

Authors: Robert J Phillips; Terry L Powley
Journal: Auton Neurosci Date: 2007-05-29 Impact factor: 3.145

3. Age-related declines in thirst and salt appetite responses in male Fischer 344×Brown Norway rats.

Authors: Robert L Thunhorst; Terry Beltz; Alan Kim Johnson
Journal: Physiol Behav Date: 2014-06-19

Review 4. Mindspan: lessons from rat models of neurocognitive aging.

Authors: Michela Gallagher; Amy M Stocker; Ming Teng Koh
Journal: ILAR J Date: 2011

5. A cross-sectional comparison of ethanol-related cytokine expression in the hippocampus of young and aged Fischer 344 rats.

Authors: Anny Gano; Tamara L Doremus-Fitzwater; Terrence Deak
Journal: Neurobiol Aging Date: 2017-03-17 Impact factor: 4.673

6. Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent pathways.

Authors: Alexander W Krug; Lena Allenhöfer; Robert Monticone; Gaia Spinetti; Michael Gekle; Mingyi Wang; Edward G Lakatta
Journal: Hypertension Date: 2010-04-26 Impact factor: 10.190

Development of animal models of aging at the National Institute of Aging.

1. A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA.

Review 2. Innervation of the gastrointestinal tract: patterns of aging.

3. Age-related declines in thirst and salt appetite responses in male Fischer 344×Brown Norway rats.

Review 4. Mindspan: lessons from rat models of neurocognitive aging.

5. A cross-sectional comparison of ethanol-related cytokine expression in the hippocampus of young and aged Fischer 344 rats.

6. Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent pathways.

7. Spatial reference memory in normal aging Fischer 344 × Brown Norway F1 hybrid rats.

8. Diaphragm muscle sarcopenia in Fischer 344 and Brown Norway rats.

9. Effects of chronic adult dietary restriction on spatial learning in the aged F344 x BN hybrid F1 rat.

10. Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains.