Literature DB >> 17918737

Formulating poly(lactide-co-glycolide) particles for plasmid DNA delivery.

Aiman O Abbas1, Maureen D Donovan, Aliasger K Salem.   

Abstract

Biodegradable poly(lactide-co-glycolide) (PLGA) particles have shown significant potential for sustained and targeted delivery of several pharmaceutical agents, including plasmid DNA (pDNA). Here, we survey current approaches to PLGA particle preparation for pDNA delivery and discuss recent progress on optimizing formulation development.

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Year:  2008        PMID： 17918737     DOI： 10.1002/jps.21215

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  26 in total

1.  Optimized dextran-polyethylenimine conjugates are efficient non-viral vectors with reduced cytotoxicity when used in serum containing environments.

Authors:  Dahai Jiang; Aliasger K Salem
Journal:  Int J Pharm       Date:  2011-10-21       Impact factor: 5.875

2.  Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA.

Authors:  Najung Kim; Dahai Jiang; Ashley M Jacobi; Kim A Lennox; Scott D Rose; Mark A Behlke; Aliasger K Salem
Journal:  Int J Pharm       Date:  2011-08-12       Impact factor: 5.875

Review 3.  Non-condensing polymeric nanoparticles for targeted gene and siRNA delivery.

Authors:  Jing Xu; Shanthi Ganesh; Mansoor Amiji
Journal:  Int J Pharm       Date:  2011-05-19       Impact factor: 5.875

4.  Combination of Nanoparticle-Delivered siRNA for Astrocyte Elevated Gene-1 (AEG-1) and All-trans Retinoic Acid (ATRA): An Effective Therapeutic Strategy for Hepatocellular Carcinoma (HCC).

Authors:  Devaraja Rajasekaran; Jyoti Srivastava; Kareem Ebeid; Rachel Gredler; Maaged Akiel; Nidhi Jariwala; Chadia L Robertson; Xue-Ning Shen; Ayesha Siddiq; Paul B Fisher; Aliasger K Salem; Devanand Sarkar
Journal:  Bioconjug Chem       Date:  2015-06-25       Impact factor: 4.774

5.  Newcastle disease virus vaccine encapsulated in biodegradable nanoparticles for mucosal delivery of a human vaccine.

Authors:  Yanwei Sun; Yang Zhang; Ci Shi; Wei Li; Gang Chen; Xiaohua Wang; Kai Zhao
Journal:  Hum Vaccin Immunother       Date:  2014       Impact factor: 3.452

Review 6.  Innovative strategies for co-delivering antigens and CpG oligonucleotides.

Authors:  Yogita Krishnamachari; Aliasger K Salem
Journal:  Adv Drug Deliv Rev       Date:  2009-01-19       Impact factor: 15.470

7.  Combinatorial co-encapsulation of hydrophobic molecules in poly(lactide-co-glycolide) microparticles.

Authors:  Abhinav P Acharya; Jamal S Lewis; Benjamin G Keselowsky
Journal:  Biomaterials       Date:  2013-02-01       Impact factor: 12.479

8.  Characterization of the transgene expression generated by branched and linear polyethylenimine-plasmid DNA nanoparticles in vitro and after intraperitoneal injection in vivo.

Authors:  Janjira Intra; Aliasger K Salem
Journal:  J Control Release       Date:  2008-04-24       Impact factor: 9.776

9.  Quantification of particle-conjugated or particle-encapsulated peptides on interfering reagent backgrounds.

Authors:  Woon Teck Yap; W Kelsey Song; Niharika Chauhan; P Nina Scalise; Radhika Agarwal; Stephen D Miller; Lonnie D Shea
Journal:  Biotechniques       Date:  2014-07-01       Impact factor: 1.993

10.  Fabrication, characterization and in vitro evaluation of poly(D,L-lactide-co-glycolide) microparticles loaded with polyamidoamine-plasmid DNA dendriplexes for applications in nonviral gene delivery.

Authors:  Janjira Intra; Aliasger K Salem
Journal:  J Pharm Sci       Date:  2010-01       Impact factor: 3.534
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