Progress from CASP6 to CASP7.

This article describes the general quality of models of three dimensional structure submitted to CASP7 and analyzes progress since the previous experiment, primarily using measures that were used in earlier analyses. Overall improvement in model accuracy compared to CASP6 is modest, but there are two developments of note: server performance has moved closer to that of humans, and there has been a significant improvement in the fraction of targets for which the best model is superior to that obtainable using knowledge of a single best template structure. (c) 2007 Wiley-Liss, Inc.