Literature DB >> 17917711

Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans.

O Tschritter, H Preissl, Y Yokoyama, F Machicao, H-U Häring, A Fritsche.   

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Year:  2007        PMID： 17917711     DOI： 10.1007/s00125-007-0839-1

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


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  9 in total

1.  Role of brain insulin receptor in control of body weight and reproduction.

Authors:  J C Brüning; D Gautam; D J Burks; J Gillette; M Schubert; P C Orban; R Klein; W Krone; D Müller-Wieland; C R Kahn
Journal:  Science       Date:  2000-09-22       Impact factor: 47.728

2.  Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes.

Authors:  Isabelle Anselme; Christine Laclef; Magali Lanaud; Ulrich Rüther; Sylvie Schneider-Maunoury
Journal:  Dev Biol       Date:  2006-12-15       Impact factor: 3.582

3.  The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study.

Authors:  Otto Tschritter; Hubert Preissl; Anita M Hennige; Michael Stumvoll; Katarina Porubska; Rebekka Frost; Hannah Marx; Benjamin Klösel; Werner Lutzenberger; Niels Birbaumer; Hans-Ulrich Häring; Andreas Fritsche
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-28       Impact factor: 11.205

4.  Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation.

Authors:  T Peters; K Ausmeier; U Rüther
Journal:  Mamm Genome       Date:  1999-10       Impact factor: 2.957

5.  The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans.

Authors:  M Stumvoll; A Fritsche; A Volk; N Stefan; A Madaus; E Maerker; A Teigeler; M Koch; F Machicao; H Häring
Journal:  Diabetes       Date:  2001-04       Impact factor: 9.461

6.  A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.

Authors:  Timothy M Frayling; Nicholas J Timpson; Michael N Weedon; Eleftheria Zeggini; Rachel M Freathy; Cecilia M Lindgren; John R B Perry; Katherine S Elliott; Hana Lango; Nigel W Rayner; Beverley Shields; Lorna W Harries; Jeffrey C Barrett; Sian Ellard; Christopher J Groves; Bridget Knight; Ann-Marie Patch; Andrew R Ness; Shah Ebrahim; Debbie A Lawlor; Susan M Ring; Yoav Ben-Shlomo; Marjo-Riitta Jarvelin; Ulla Sovio; Amanda J Bennett; David Melzer; Luigi Ferrucci; Ruth J F Loos; Inês Barroso; Nicholas J Wareham; Fredrik Karpe; Katharine R Owen; Lon R Cardon; Mark Walker; Graham A Hitman; Colin N A Palmer; Alex S F Doney; Andrew D Morris; George Davey Smith; Andrew T Hattersley; Mark I McCarthy
Journal:  Science       Date:  2007-04-12       Impact factor: 47.728

7.  A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

Authors:  Laura J Scott; Karen L Mohlke; Lori L Bonnycastle; Cristen J Willer; Yun Li; William L Duren; Michael R Erdos; Heather M Stringham; Peter S Chines; Anne U Jackson; Ludmila Prokunina-Olsson; Chia-Jen Ding; Amy J Swift; Narisu Narisu; Tianle Hu; Randall Pruim; Rui Xiao; Xiao-Yi Li; Karen N Conneely; Nancy L Riebow; Andrew G Sprau; Maurine Tong; Peggy P White; Kurt N Hetrick; Michael W Barnhart; Craig W Bark; Janet L Goldstein; Lee Watkins; Fang Xiang; Jouko Saramies; Thomas A Buchanan; Richard M Watanabe; Timo T Valle; Leena Kinnunen; Gonçalo R Abecasis; Elizabeth W Pugh; Kimberly F Doheny; Richard N Bergman; Jaakko Tuomilehto; Francis S Collins; Michael Boehnke
Journal:  Science       Date:  2007-04-26       Impact factor: 47.728

8.  Variation in FTO contributes to childhood obesity and severe adult obesity.

Authors:  Christian Dina; David Meyre; Sophie Gallina; Emmanuelle Durand; Antje Körner; Peter Jacobson; Lena M S Carlsson; Wieland Kiess; Vincent Vatin; Cecile Lecoeur; Jérome Delplanque; Emmanuel Vaillant; François Pattou; Juan Ruiz; Jacques Weill; Claire Levy-Marchal; Fritz Horber; Natascha Potoczna; Serge Hercberg; Catherine Le Stunff; Pierre Bougnères; Peter Kovacs; Michel Marre; Beverley Balkau; Stéphane Cauchi; Jean-Claude Chèvre; Philippe Froguel
Journal:  Nat Genet       Date:  2007-05-13       Impact factor: 38.330

9.  Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Authors:  Angelo Scuteri; Serena Sanna; Wei-Min Chen; Manuela Uda; Giuseppe Albai; James Strait; Samer Najjar; Ramaiah Nagaraja; Marco Orrú; Gianluca Usala; Mariano Dei; Sandra Lai; Andrea Maschio; Fabio Busonero; Antonella Mulas; Georg B Ehret; Ashley A Fink; Alan B Weder; Richard S Cooper; Pilar Galan; Aravinda Chakravarti; David Schlessinger; Antonio Cao; Edward Lakatta; Gonçalo R Abecasis
Journal:  PLoS Genet       Date:  2007-07       Impact factor: 5.917
  9 in total
  39 in total

1.  Is FTO a type 2 diabetes susceptibility gene?

Authors:  D Meyre
Journal:  Diabetologia       Date:  2012-04       Impact factor: 10.122

2.  Insulin effects on beta and theta activity in the human brain are differentially affected by ageing.

Authors:  O Tschritter; A M Hennige; H Preissl; Y Grichisch; K Kirchhoff; K Kantartzis; F Machicao; A Fritsche; H-U Häring
Journal:  Diabetologia       Date:  2008-11-19       Impact factor: 10.122

Review 3.  Genetics of metabolic syndrome.

Authors:  Alena Stančáková; Markku Laakso
Journal:  Rev Endocr Metab Disord       Date:  2014-12       Impact factor: 6.514

Review 4.  Metabolic neuroimaging of the brain in diabetes mellitus and hypoglycaemia.

Authors:  Yee-Seun Cheah; Stephanie A Amiel
Journal:  Nat Rev Endocrinol       Date:  2012-06-26       Impact factor: 43.330

Review 5.  From monogenic to polygenic obesity: recent advances.

Authors:  Anke Hinney; Carla I G Vogel; Johannes Hebebrand
Journal:  Eur Child Adolesc Psychiatry       Date:  2010-02-03       Impact factor: 4.785

6.  The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China.

Authors:  Bo Xi; Yue Shen; Meixian Zhang; Xin Liu; Xiaoyuan Zhao; Lijun Wu; Hong Cheng; Dongqing Hou; Klaus Lindpaintner; Lisheng Liu; Jie Mi; Xingyu Wang
Journal:  BMC Med Genet       Date:  2010-07-05       Impact factor: 2.103

Review 7.  Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums.

Authors:  Steven E Arnold; Zoe Arvanitakis; Shannon L Macauley-Rambach; Aaron M Koenig; Hoau-Yan Wang; Rexford S Ahima; Suzanne Craft; Sam Gandy; Christoph Buettner; Luke E Stoeckel; David M Holtzman; David M Nathan
Journal:  Nat Rev Neurol       Date:  2018-01-29       Impact factor: 42.937

8.  Interaction between the obesity-risk gene FTO and the dopamine D2 receptor gene ANKK1/TaqIA on insulin sensitivity.

Authors:  Martin Heni; Stephanie Kullmann; Emma Ahlqvist; Robert Wagner; Fausto Machicao; Harald Staiger; Hans-Ulrich Häring; Peter Almgren; Leif C Groop; Dana M Small; Andreas Fritsche; Hubert Preissl
Journal:  Diabetologia       Date:  2016-09-06       Impact factor: 10.122

9.  Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders?

Authors:  M Hallschmid; B Schultes
Journal:  Diabetologia       Date:  2009-08-25       Impact factor: 10.122

10.  Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.

Authors:  Louise G Grunnet; Emma Nilsson; Charlotte Ling; Torben Hansen; Oluf Pedersen; Leif Groop; Allan Vaag; Pernille Poulsen
Journal:  Diabetes       Date:  2009-07-08       Impact factor: 9.461
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