Literature DB >> 1791484

Novel cytotoxic principles of Formosan Ganoderma lucidum.

C N Lin1, W P Tome, S J Won.   

Abstract

Two new steryl esters, ergosta-7,22-dien-3 beta-yl linoleate [1] and 5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-yl linoleate [3], and a novel steroid, ergosta-7,22-diene- 3 beta,3 alpha,9 alpha-triol [5], have been isolated from the fruiting bodies of Formosan Ganoderma lucidum and characterized. A new lanostanoid, 3 beta-hydroxy-26-oxo-5 alpha-lanosta- 8,24-dien-11-one, and the new steroid exhibited potent inhibition of KB cells and human PLC/PRF/5 cells in vitro.

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Year:  1991        PMID： 1791484     DOI： 10.1021/np50076a012

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

Review 1.  The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis.

Authors:  Chia-Jui Weng; Gow-Chin Yen
Journal:  Clin Exp Metastasis       Date:  2010-05-12       Impact factor: 5.150

2.  Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum.

Authors:  Qun Zhang; Feng Zuo; Norio Nakamura; Chao-Mei Ma; Masao Hattori
Journal:  J Nat Med       Date:  2009-05-01       Impact factor: 2.343

3.  Identifying the "Mushroom of Immortality": Assessing the Ganoderma Species Composition in Commercial Reishi Products.

Authors:  Andrew L Loyd; Brantlee S Richter; Michelle A Jusino; Camille Truong; Matthew E Smith; Robert A Blanchette; Jason A Smith
Journal:  Front Microbiol       Date:  2018-07-16       Impact factor: 5.640

4.  Total Syntheses and Biological Evaluation of the Ganoderma lucidum Alkaloids Lucidimines B and C.

Authors:  Yongsheng Chen; Ping Lan
Journal:  ACS Omega       Date:  2018-03-26

5.  Secondary Metabolites from Hericium erinaceus and Their Anti-Inflammatory Activities.

Authors:  Guangbo Xie; Lan Tang; Yu Xie; Liyuan Xie
Journal:  Molecules       Date:  2022-03-27       Impact factor: 4.411

6.  Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms.

Authors:  Jie Liu; Kuniyoshi Shimizu; Akinobu Tanaka; Wakako Shinobu; Koichiro Ohnuki; Takanori Nakamura; Ryuichiro Kondo
Journal:  Sci Rep       Date:  2012-11-30       Impact factor: 4.379

7.  Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma with Ganoderma lucidum Extracts.

Authors:  Sora Huh; Seulki Lee; Su Jin Choi; Zhexue Wu; Jae-Han Cho; Lina Kim; Yu Su Shin; Byung Woog Kang; Jong Gwang Kim; Kwanghyeon Liu; Hyosun Cho; Hyojeung Kang
Journal:  Molecules       Date:  2019-10-24       Impact factor: 4.411
  7 in total

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