Literature DB >> 17914242

The next step in biology: a periodic table?

Pawan K Dhar1.   

Abstract

Systems biology is an approach to explain the behaviour of a system in relation to its individual components. Synthetic biology uses key hierarchical and modular concepts of systems biology to engineer novel biological systems. In my opinion the next step in biology is to use molecule-to-phenotype data using these approaches and integrate them in the form a periodic table. A periodic table in biology would provide chassis to classify, systematize and compare diversity of component properties vis-a-vis system behaviour. Using periodic table it could be possible to compute higher- level interactions from component properties. This paper examines the concept of building a bio-periodic table using protein fold as the fundamental unit.

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Year:  2007        PMID: 17914242     DOI: 10.1007/s12038-007-0099-8

Source DB:  PubMed          Journal:  J Biosci        ISSN: 0250-5991            Impact factor:   1.826


  2 in total

1.  Enabling the new biology of the 21(st) century.

Authors:  Pawan K Dhar; Ron Weiss
Journal:  Syst Synth Biol       Date:  2007-03

2.  Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotides.

Authors:  Hamilton O Smith; Clyde A Hutchison; Cynthia Pfannkoch; J Craig Venter
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-02       Impact factor: 11.205

  2 in total
  4 in total

1.  An attempt to construct a (general) mathematical framework to model biological "context-dependence".

Authors:  Anirban Banerji
Journal:  Syst Synth Biol       Date:  2013-08-28

2.  Laws of biology: why so few?

Authors:  Pawan K Dhar; Alessandro Giuliani
Journal:  Syst Synth Biol       Date:  2009-12-29

3.  Positioning genomics in biology education: content mapping of undergraduate biology textbooks.

Authors:  Naomi L B Wernick; Eric Ndung'u; Dominique Haughton; Fred D Ledley
Journal:  J Microbiol Biol Educ       Date:  2014-12-15

4.  Will systems biology offer new holistic paradigms to life sciences?

Authors:  Filippo Conti; Maria Cristina Valerio; Joseph P Zbilut; Alessandro Giuliani
Journal:  Syst Synth Biol       Date:  2008-05-30
  4 in total

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