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Literature DB >> 17914166

Role of ascorbic acid in scavenging free radicals and lead toxicity from biosystems.

Shabbir A Tariq¹.
1. satariq900@yahoo.com

Abstract

Free radicals are reactive species that are responsible for damaging normal cells and creating diseases in humans. Antioxidants from natural resources or as supplements can scavenge these radicals. A MedLine search indicates that vitamin C is the most investigated antioxidant responsible for the elimination of free radicals. Its chelating property for the removal of neurotoxic lead, which creates oxidative stress in the human biosystem, was investigated and results indicate its great potential as a lead-detoxifying agent.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2007 PMID： 17914166 DOI： 10.1007/s12033-007-0045-x

Source DB: PubMed Journal: Mol Biotechnol ISSN： 1073-6085 Impact factor: 2.695

29 in total

1. Elevated blood lead levels in Karachi children.

Authors: F White; M H Rahbar; M Agboatwalla; S Luby; A Iqbal; S Hozhabri
Journal: Bull World Health Organ Date: 2001 Impact factor: 9.408

2. Long-term effect of combined vitamins E and C on coronary and peripheral endothelial function.

Authors: Scott Kinlay; Dominik Behrendt; James C Fang; Danielle Delagrange; Jason Morrow; Joseph L Witztum; Nader Rifai; Andrew P Selwyn; Mark A Creager; Peter Ganz
Journal: J Am Coll Cardiol Date: 2004-02-18 Impact factor: 24.094

3. Effect of chronic oral supplementation with vitamins on the endothelial function in chronic smokers.

Authors: Bonpei Takase; Hirokuni Etsuda; Yoshihiro Matsushima; Makoto Ayaori; Hiroyuki Kusano; Akira Hamabe; Akimi Uehata; Fumitaka Ohsuzu; Masayuki Ishihara; Akira Kurita
Journal: Angiology Date: 2004 Nov-Dec Impact factor: 3.619

4. Factors associated with elevated blood lead concentrations in children in Karachi, Pakistan.

Authors: Mohammad Hossein Rahbar; Franklin White; Mubina Agboatwalla; Siroos Hozhabri; Stephen Luby
Journal: Bull World Health Organ Date: 2002-11-28 Impact factor: 9.408

5. Oral vitamin C and endothelial function in smokers: short-term improvement, but no sustained beneficial effect.

Authors: O T Raitakari; M R Adams; R J McCredie; K A Griffiths; R Stocker; D S Celermajer
Journal: J Am Coll Cardiol Date: 2000-05 Impact factor: 24.094

6. Renal vascular function in hypercholesterolemia is preserved by chronic antioxidant supplementation.

Authors: John M Stulak; Amir Lerman; Martin Rodriguez Porcel; James A Caccitolo; J Carlos Romero; Hartzell V Schaff; Claudio Napoli; Lilach O Lerman
Journal: J Am Soc Nephrol Date: 2001-09 Impact factor: 10.121

7. Acute effects of vitamin C on platelet responsiveness to nitric oxide donors and endothelial function in patients with chronic heart failure.

Authors: G R Ellis; R A Anderson; Y Y Chirkov; J Morris-Thurgood; S K Jackson; M J Lewis; J D Horowitz; M P Frenneaux
Journal: J Cardiovasc Pharmacol Date: 2001-05 Impact factor: 3.105

8. Effects of vitamin supplementation on microcirculatory disturbance in hemodialysis patients without peripheral arterial disease.

Authors: M Sato; Y Matsumoto; H Morita; H Takemura; K Shimoi; I Amano
Journal: Clin Nephrol Date: 2003-07 Impact factor: 0.975

9. Long-term antioxidant intervention improves myocardial microvascular function in experimental hypertension.

Authors: Martin Rodriguez-Porcel; Joerg Herrman; Alejandro R Chade; James D Krier; Jerome F Breen; Amir Lerman; Lilach O Lerman
Journal: Hypertension Date: 2004-01-12 Impact factor: 10.190

10. Beneficial effects of antioxidant vitamins on the stenotic kidney.

Authors: Alejandro R Chade; Martin Rodriguez-Porcel; Joerg Herrmann; James D Krier; Xiangyang Zhu; Amir Lerman; Lilach O Lerman
Journal: Hypertension Date: 2003-08-18 Impact factor: 10.190

9 in total

1. Association of blood lead (Pb) and plasma homocysteine: a cross sectional survey in Karachi, Pakistan.

Authors: Mohsin Yakub; Mohammad Perwaiz Iqbal
Journal: PLoS One Date: 2010-07-21 Impact factor: 3.240

2. Protective effect of curcumin on lead acetate-induced testicular toxicity in Wistar rats.

Authors: Sri Agus Sudjarwo; Giftania Wardani Sudjarwo
Journal: Res Pharm Sci Date: 2017-10

3. The protective effect of Rubia cordifolia against lead nitrate-induced immune response impairment and kidney oxidative damage.

Authors: Shweta Lodi; Veena Sharma; Leena Kansal
Journal: Indian J Pharmacol Date: 2011-07 Impact factor: 1.200