Literature DB >> 17912074

Surgical therapy for osteonecotic lesions of the jaws in patients in therapy with bisphosphonates.

Gianluigi Longobardi1, Roberto Boniello, Giulio Gasparini, Immacolata Pagano, Sandro Pelo.   

Abstract

OBJECTIVE: Surgical therapy to improve the symptoms and the lesions in osteonecrosis (ON) of the jaws in patients in therapy with bisphosphonates.
DESIGN: to evaluate the patient's therapeutic protocols, performance status, and factors promoting ON to prevent surgical failure.
MATERIALS AND METHODS: 18 patients affected by osteonecrotic lesions of the jaws associated to BF, were treated by surgery.
RESULTS: The results were recorded after 6 months. All the patients showed improvement of symptoms, in particular the pain. In addition, all the patients referred to a sensation of fresh and clean mouth, the disappearance of fetor ex ore, and a healthy mouth.
CONCLUSIONS: The management and the resolution of BF osteonecrotic lesions is arguable and complex because in most cases, the patients are affected by oncologic disease when the better approach is prevention, but when the ON lesion is clear, surgery can improve the symptoms and in some cases, it can be resolute. To prevent surgical failure, it can be useful to evaluate the patient's therapeutic protocols, performance status, and factors promoting ON.

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Year:  2007        PMID: 17912074     DOI: 10.1097/scs.0b013e3180f611ef

Source DB:  PubMed          Journal:  J Craniofac Surg        ISSN: 1049-2275            Impact factor:   1.046


  4 in total

1.  Surgical approach with Er:YAG laser on osteonecrosis of the jaws (ONJ) in patients under bisphosphonate therapy (BPT).

Authors:  Paolo Vescovi; Maddalena Manfredi; Elisabetta Merigo; Marco Meleti; Carlo Fornaini; Jean-Paul Rocca; Samir Nammour
Journal:  Lasers Med Sci       Date:  2009-06-19       Impact factor: 3.161

2.  Pathological fracture of the coronoid process secondary to medication-related osteonecrosis of the jaw (MRONJ).

Authors:  Adam Jowett; Anwer Abdullakutty; Malcolm Bailey
Journal:  Int J Surg Case Rep       Date:  2015-03-17

Review 3.  Analysis of different therapeutic protocols for osteonecrosis of the jaw associated with oral and intravenous bisphosphonates.

Authors:  E-B Bermúdez-Bejarano; M-Á Serrera-Figallo; A Gutiérrez-Corrales; M-M Romero-Ruiz; R Castillo-de-Oyagüe; J-L Gutiérrez-Pérez; G Machuca-Portillo; D Torres-Lagares
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2017-01-01

4.  Platelet rich plasma in the treatment of bisphosphonate-related osteonecrosis of the jaw: personal experience and review of the literature.

Authors:  F Longo; A Guida; C Aversa; E Pavone; G Di Costanzo; L Ramaglia; F Ionna
Journal:  Int J Dent       Date:  2014-06-10
  4 in total

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