Literature DB >> 17910526

Contrasting roles of IFN-gamma in murine models of autoimmune thyroid diseases.

Yujiang Fang1, Shiguang Yu, Helen Braley-Mullen.   

Abstract

Interferon-gamma (IFN-gamma), a prototypic proinflammatory cytokine produced by several different cell types, including the Th1 subset of CD4(+) T cells, plays an important role in inflammation and autoimmune diseases. This review focuses on the varied and often contrasting roles of IFN-gamma in three murine models of autoimmune thyroid disease, experimentally induced autoimmune thyroiditis, the model of iodine-induced spontaneous autoimmune thyroiditis in NOD.H-2h4 mice and several different murine models of Graves' disease.

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Year:  2007        PMID： 17910526     DOI： 10.1089/thy.2007.0261

Source DB:  PubMed          Journal:  Thyroid        ISSN： 1050-7256            Impact factor:   6.568


  10 in total

1.  TGF-β promotes proliferation of thyroid epithelial cells in IFN-γ(-/-) mice by down-regulation of p21 and p27 via AKT pathway.

Authors:  Yujiang Fang; Shiguang Yu; Helen Braley-Mullen
Journal:  Am J Pathol       Date:  2011-11-24       Impact factor: 4.307

2.  A critical role for TRAIL in resolution of granulomatous experimental autoimmune thyroiditis.

Authors:  Y Fang; G C Sharp; H Yagita; H Braley-Mullen
Journal:  J Pathol       Date:  2008-12       Impact factor: 7.996

3.  Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice.

Authors:  Yujiang Fang; Kemin Chen; Daniel A Jackson; Gordon C Sharp; Helen Braley-Mullen
Journal:  Immunology       Date:  2009-10-21       Impact factor: 7.397

4.  Influence of signal transducer and activator of transcription-1 signaling on thyroid morphology and function.

Authors:  Hiroaki J Kimura; Roberto Rocchi; Melissa A Landek-Salgado; Koichi Suzuki; Cindy Y Chen; Miho Kimura; Noel R Rose; Patrizio Caturegli
Journal:  Endocrinology       Date:  2009-03-26       Impact factor: 4.736

5.  Interleukin-10 promotes resolution of granulomatous experimental autoimmune thyroiditis.

Authors:  Yujiang Fang; Gordon C Sharp; Helen Braley-Mullen
Journal:  Am J Pathol       Date:  2008-05-08       Impact factor: 4.307

Review 6.  Toxicology of autoimmune diseases.

Authors:  K Michael Pollard; Per Hultman; Dwight H Kono
Journal:  Chem Res Toxicol       Date:  2010-03-15       Impact factor: 3.739

7.  IFN{gamma} regulates retinal pigment epithelial fluid transport.

Authors:  Rong Li; Arvydas Maminishkis; Tina Banzon; Qin Wan; Stephen Jalickee; Shan Chen; Sheldon S Miller
Journal:  Am J Physiol Cell Physiol       Date:  2009-09-30       Impact factor: 4.249

8.  Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways.

Authors:  Thea Morris; Melanie Stables; Paul Colville-Nash; Justine Newson; Geoffrey Bellingan; Patricia M de Souza; Derek W Gilroy
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-26       Impact factor: 11.205

9.  Cell-type-specific expression of STAT transcription factors in tissue samples from patients with lymphocytic thyroiditis.

Authors:  Julia Staab; Peter J Barth; Thomas Meyer
Journal:  Endocr Pathol       Date:  2012-09       Impact factor: 3.943

10.  Cytometric evaluation of intracellular IFN-γ and IL-4 levels in thyroid follicular cells from patients with autoimmune thyroid diseases.

Authors:  Artur Bossowski; Jerzy Harasymczuk; Anna Moniuszko; Anna Bossowska; Maciej Hilczer; Karol Ratomski
Journal:  Thyroid Res       Date:  2011-09-23
  10 in total

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