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Literature DB >> 17910011

Biologically stable 2-5A analogues containing 3'-O,4'-C-bridged adenosine as potent RNase L agonists.

Koji Morita¹, Masakatsu Kaneko, Satoshi Obika, Takeshi Imanishi, Yukio Kitade, Makoto Koizumi.

Abstract

Entities: Chemical Gene

Mesh：

Substances：

Year: 2007 PMID： 17910011 DOI： 10.1002/cmdc.200700150

Source DB: PubMed Journal: ChemMedChem ISSN： 1860-7179 Impact factor: 3.466

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2 in total

1. Recognition of 2',5'-linked oligoadenylates by human ribonuclease L: molecular dynamics study.

Authors: Kamil Maláč; Ivan Barvík
Journal: J Mol Model Date: 2014-03-16 Impact factor: 1.810

2. Renadirsen, a Novel 2'OMeRNA/ENA^® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo.

Authors: Kentaro Ito; Hideo Takakusa; Masayo Kakuta; Akira Kanda; Nana Takagi; Hiroyuki Nagase; Nobuaki Watanabe; Daigo Asano; Ryoya Goda; Takeshi Masuda; Akifumi Nakamura; Yoshiyuki Onishi; Toshio Onoda; Makoto Koizumi; Yasuhiro Takeshima; Masafumi Matsuo; Kiyosumi Takaishi
Journal: Curr Issues Mol Biol Date: 2021-09-25 Impact factor: 2.976

2 in total

Biologically stable 2-5A analogues containing 3'-O,4'-C-bridged adenosine as potent RNase L agonists.

1. Recognition of 2',5'-linked oligoadenylates by human ribonuclease L: molecular dynamics study.

2. Renadirsen, a Novel 2'OMeRNA/ENA® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo.

2. Renadirsen, a Novel 2'OMeRNA/ENA^® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo.