Literature DB >> 17909497

An efficient and rapid synthetic route to biologically interesting pyranochalcone natural products.

Yong Rok Lee1, Xue Wang, Likai Xia.   

Abstract

An efficient and concise total synthesis of naturally occurring pyranochalcones was achieved from readily available 2,4-dihydroxyacetophenone and 2,4-dihydroxy-6-methoxyacetophenone. The key steps in the synthetic strategy were ethylenediamine diacetate-catalyzed benzopyran formation and aldol reactions.

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Year:  2007        PMID: 17909497      PMCID: PMC6149329          DOI: 10.3390/12071420

Source DB:  PubMed          Journal:  Molecules        ISSN: 1420-3049            Impact factor:   4.411


  9 in total

1.  Selenium-Based Solid-Phase Synthesis of Benzopyrans I: Applications to Combinatorial Synthesis of Natural Products.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-02       Impact factor: 15.336

2.  New bioactive flavonoids and stilbenes in cubé resin insecticide.

Authors:  N Fang; J E Casida
Journal:  J Nat Prod       Date:  1999-02       Impact factor: 4.050

3.  Antifeedant and antifungal activity of chromene compounds isolated from Blepharispermum subsessile.

Authors:  S K Agarwal; S Verma; S S Singh; A K Tripathi; Z K Khan; S Kumar
Journal:  J Ethnopharmacol       Date:  2000-07       Impact factor: 4.360

4.  Antinephritis and radical scavenging activity of prenylflavonoids.

Authors:  Toshio Fukai; Kazue Satoh; Taro Nomura; Hiroshi Sakagami
Journal:  Fitoterapia       Date:  2003-12       Impact factor: 2.882

5.  Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production.

Authors:  Ah-Reum Han; You-Jin Kang; Tri Windono; Sang Kook Lee; Eun-Kyoung Seo
Journal:  J Nat Prod       Date:  2006-04       Impact factor: 4.050

6.  C-prenylflavonoids from roots of Tephrosia tunicata.

Authors:  C C Andrei; D T Ferreira; M Faccione; L A de Moraes; M G de Carvalho; R Braz-Filho
Journal:  Phytochemistry       Date:  2000-12       Impact factor: 4.072

7.  Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines.

Authors:  C L Miranda; J F Stevens; A Helmrich; M C Henderson; R J Rodriguez; Y H Yang; M L Deinzer; D W Barnes; D R Buhler
Journal:  Food Chem Toxicol       Date:  1999-04       Impact factor: 6.023

8.  A new 5-lipoxygenase selective inhibitor derived from Artocarpus communis strongly inhibits arachidonic acid-induced ear edema.

Authors:  Y Koshihara; Y Fujimoto; H Inoue
Journal:  Biochem Pharmacol       Date:  1988-06-01       Impact factor: 5.858

9.  A convenient and biogenetic type synthesis of few naturally occurring chromeno dihydrochalcones and their in vitro antileishmanial activity.

Authors:  Tadigoppula Narender; Suman Gupta
Journal:  Bioorg Med Chem Lett       Date:  2004-08-02       Impact factor: 2.823

  9 in total
  1 in total

1.  Computational analysis of the activity of pongachalcone I against highly resistant bacteria Pseudomonas putida.

Authors:  Satya B Paul; Sudip Choudhury
Journal:  Bioinformation       Date:  2010-04-30
  1 in total

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