Literature DB >> 17909490

Synthesis of 4-aryl substituted 3,4-dihydropyrimidinones using silica-chloride under solvent free conditions.

Hitendra N Karade1, Manisha Sathe, M P Kaushik.   

Abstract

This paper describes an improved procedure for the efficient and facile synthesis of 4-aryl substituted 3, 4-dihydropyrimidinones under mild reaction conditions with excellent yields using inexpensive silica chloride under solvent free conditions.

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Year:  2007        PMID： 17909490      PMCID： PMC6149431          DOI： 10.3390/12071341

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  5 in total

1.  Indium(III) chloride-catalyzed one-pot synthesis of dihydropyrimidinones by a three-component coupling of 1,3-dicarbonyl compounds, aldehydes, and urea: an improved procedure for the Biginelli reaction.

Authors:  B C Ranu; A Hajra; U Jana
Journal:  J Org Chem       Date:  2000-09-22       Impact factor: 4.354

2.  Reactions of silica chloride (SiO(2)Cl)/DMSO, a heterogeneous system for the facile regeneration of carbonyl compounds from thioacetals and ring-expansion annelation of cyclic thioacetals.

Authors:  Habib Firouzabadi; Nasser Iranpoor; Hassan Hazarkhani; Babak Karimi
Journal:  J Org Chem       Date:  2002-04-19       Impact factor: 4.354

3.  A Reexamination of the Mechanism of the Biginelli Dihydropyrimidine Synthesis. Support for an N-Acyliminium Ion Intermediate(1).

Authors:  C. Oliver Kappe
Journal:  J Org Chem       Date:  1997-10-17       Impact factor: 4.354

4.  Lanthanide triflate catalyzed Biginelli reaction. one-pot synthesis of dihydropyrimidinones under solvent-free conditions.

Authors:  Y Ma; C Qian; L Wang; M Yang
Journal:  J Org Chem       Date:  2000-06-16       Impact factor: 4.354

5.  Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents.

Authors:  K S Atwal; B N Swanson; S E Unger; D M Floyd; S Moreland; A Hedberg; B C O'Reilly
Journal:  J Med Chem       Date:  1991-02       Impact factor: 7.446
  5 in total
  4 in total

1.  Eutectic salt catalyzed environmentally benign and highly efficient Biginelli reaction.

Authors:  Najmadin Azizi; Sahar Dezfuli; Mohmmad Mahmoodi Hahsemi
Journal:  ScientificWorldJournal       Date:  2012-04-29

2.  Crystal structure of ethyl 6-methyl-2-oxo-4-(3,4,5-tri-meth-oxy-phen-yl)-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate.

Authors:  J J Novina; G Vasuki; M Suresh; M Syed Ali Padusha
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-02-25

3.  Ultrasound-assisted synthesis of novel 4-(2-phenyl-1,2,3-triazol-4-yl)-3,4-dihydropyrimidin-(1H)-(thio)ones catalyzed by Sm(ClO(4))(3).

Authors:  Chen-Jiang Liu; Ji-De Wang
Journal:  Molecules       Date:  2010-03-24       Impact factor: 4.411

4.  Copper(II) sulfamate: an efficient catalyst for the one-pot synthesis of 3,4-dihydropyrimidine-2(1H)-ones and thiones.

Authors:  Chen-Jiang Liu; Ji-De Wang
Journal:  Molecules       Date:  2009-02-13       Impact factor: 4.411
  4 in total

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