Literature DB >> 17909172

A case report of the treatment of diabetic foot ulcers using a sodium hyaluronate and iodine complex.

Lubos Sobotka1, Alena Smahelova, Jana Pastorova, Marie Kusalova.   

Abstract

Diabetic foot ulcers are difficult to heal due to defects in local microvasculature and persistent, concomitant infection. Despite the best medical care, amputation is often a management option for this problem. The authors have developed a new and unique system for wound treatment, which is based on a combination of high molecular weight sodium hyaluronate with an iodine complex-Hyiodine (Contipro C, Dolní Dobrouc, Czech Republic). In this case report, the authors present an observational study on a series of patients with diabetic foot disease with nonhealing wounds treated with Hyiodine. The effect of the HA-iodine complex was studied on 18 patients suffering from complicated foot diabetic wounds. The HA-iodine complex was either spread directly over the wound, or more frequently, gauze was immersed in the HA-iodine complex and then put on/into the wound. Then several layers of dry gauze covered the wound. This dressing was changed every 24 hours. Wound healing was monitored daily, and wound pictures were taken each second week. Clinical improvement was observed in the majority. This suggests that the HA-iodine complex dressing has potential that needs to be developed from controlled studies.

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Year:  2007        PMID: 17909172     DOI: 10.1177/1534734607304684

Source DB:  PubMed          Journal:  Int J Low Extrem Wounds        ISSN: 1534-7346            Impact factor:   2.057


  4 in total

1.  The role of hyaluronan in wound healing.

Authors:  Joseph S Frenkel
Journal:  Int Wound J       Date:  2012-08-14       Impact factor: 3.315

2.  [Hyaluronan as a key for accelerated wound healing in human 3D full thickness skin models].

Authors:  L Rüther; L Bolke; G R Schlippe; W A Voss
Journal:  Hautarzt       Date:  2017-12       Impact factor: 0.751

3.  The role of CD44 in cutaneous inflammation.

Authors:  Mona Man; Peter M Elias; Wenyan Man; Yan Wu; Lilly Y W Bourguignon; Kenneth R Feingold; Mao-Qiang Man
Journal:  Exp Dermatol       Date:  2009-03-26       Impact factor: 3.960

4.  Management of post-surgical infection of onychocryptosis with topical application of hyaluronic acid versus antibacterial ointments.

Authors:  Almudena Núñez Fernández; Alvaro Gómez-Carrión; Ignacio Zaragoza-García; Carlos Martínez Sebastián; Paola Sanz Wozniak; Arturo Gómez Lara; Arturo Saura-Sempere; Rubén Sánchez-Gómez
Journal:  Heliyon       Date:  2022-08-08
  4 in total

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