OBJECTIVE: To perform a meta-analysis of randomized controlled trials of cinnamon to better characterize its impact on glucose and plasma lipids. RESEARCH DESIGN AND METHODS: A systematic literature search through July 2007 was conducted to identify randomized placebo-controlled trials of cinnamon that reported data on A1C, fasting blood glucose (FBG), or lipid parameters. The mean change in each study end point from baseline was treated as a continuous variable, and the weighted mean difference was calculated as the difference between the mean value in the treatment and control groups. A random-effects model was used. RESULTS: Five prospective randomized controlled trials (n = 282) were identified. Upon meta-analysis, the use of cinnamon did not significantly alter A1C, FBG, or lipid parameters. Subgroup and sensitivity analyses did not significantly change the results. CONCLUSIONS: Cinnamon does not appear to improve A1C, FBG, or lipid parameters in patients with type 1 or type 2 diabetes.
OBJECTIVE: To perform a meta-analysis of randomized controlled trials of cinnamon to better characterize its impact on glucose and plasma lipids. RESEARCH DESIGN AND METHODS: A systematic literature search through July 2007 was conducted to identify randomized placebo-controlled trials of cinnamon that reported data on A1C, fasting blood glucose (FBG), or lipid parameters. The mean change in each study end point from baseline was treated as a continuous variable, and the weighted mean difference was calculated as the difference between the mean value in the treatment and control groups. A random-effects model was used. RESULTS: Five prospective randomized controlled trials (n = 282) were identified. Upon meta-analysis, the use of cinnamon did not significantly alter A1C, FBG, or lipid parameters. Subgroup and sensitivity analyses did not significantly change the results. CONCLUSIONS:Cinnamon does not appear to improve A1C, FBG, or lipid parameters in patients with type 1 or type 2 diabetes.
Authors: Robert W Allen; Emmanuelle Schwartzman; William L Baker; Craig I Coleman; Olivia J Phung Journal: Ann Fam Med Date: 2013 Sep-Oct Impact factor: 5.166
Authors: Kamal A A Mohammed; Helmy M S Ahmed; Hafiza A Sharaf; Aziza A El-Nekeety; Sekena H Abdel-Aziem; Fathy M Mehaya; Mosaad A Abdel-Wahhab Journal: Environ Sci Pollut Res Int Date: 2019-12-13 Impact factor: 4.223