Literature DB >> 17908554

Estrogen and bone: osteoclasts take center stage.

Deborah V Novack1.   

Abstract

Loss of estrogen at menopause causes osteoporosis in many women, but estrogen's relevant cellular target in this process has remained unclear. In a recent study in Cell, Kato and colleagues (Nakamura et al., 2007) selectively ablate estrogen receptor alpha in osteoclasts and demonstrate that estrogen directly induces osteoclast apoptosis.

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Year:  2007        PMID： 17908554     DOI： 10.1016/j.cmet.2007.09.007

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  9 in total

1.  Association between ER-α polymorphisms and bone mineral density in patients with Turner syndrome subjected to estroprogestagen treatment--a pilot study.

Authors:  Elżbieta Sowińska-Przepiera; Elżbieta Andrysiak-Mamos; Kornel Chełstowski; Grażyna Adler; Zbigniew Friebe; Anhelli Syrenicz
Journal:  J Bone Miner Metab       Date:  2011-01-27       Impact factor: 2.626

2.  The lateral meningocele syndrome mutation causes marked osteopenia in mice.

Authors:  Ernesto Canalis; Jungeun Yu; Lauren Schilling; Siu-Pok Yee; Stefano Zanotti
Journal:  J Biol Chem       Date:  2018-07-24       Impact factor: 5.157

3.  Oestrogen receptor positive breast cancer metastasis to bone: inhibition by targeting the bone microenvironment in vivo.

Authors:  I Holen; M Walker; F Nutter; A Fowles; C A Evans; C L Eaton; P D Ottewell
Journal:  Clin Exp Metastasis       Date:  2015-11-19       Impact factor: 5.150

4.  Gender-independent efficacy of mesenchymal stem cell therapy in sex hormone-deficient bone loss via immunosuppression and resident stem cell recovery.

Authors:  Bing-Dong Sui; Ji Chen; Xin-Yi Zhang; Tao He; Pan Zhao; Chen-Xi Zheng; Meng Li; Cheng-Hu Hu; Yan Jin
Journal:  Exp Mol Med       Date:  2018-12-17       Impact factor: 8.718

5.  Pantoprazole (PPZ) Inhibits RANKL-Induced Osteoclast Formation and Function In Vitro and Prevents Lipopolysaccharide- (LPS-) Induced Inflammatory Calvarial Bone Loss In Vivo.

Authors:  Yu-Xi Li; Fu-Chao Chen; Ting Liu; Zhao-Peng Cai; Keng Chen; Guo-Xue Tang; Jun-Shen Huang; Xiang-Ge Liu; Jia-Jun Huang; Peng Wang; Yu-Wei Liang; Lin Huang
Journal:  Stem Cells Int       Date:  2020-11-28       Impact factor: 5.443

6.  Bone selective protective effect of a novel bone-seeking estrogen on trabecular bone in ovariectomized rats.

Authors:  Qiang Zhao; Xiaodong Liu; Lianfang Zhang; Xing Shen; Jin Qi; Jinshen Wang; Niandong Qian; Lianfu Deng
Journal:  Calcif Tissue Int       Date:  2013-06-19       Impact factor: 4.333

7.  Pregnenolone Inhibits Osteoclast Differentiation and Protects Against Lipopolysaccharide-Induced Inflammatory Bone Destruction and Ovariectomy-Induced Bone Loss.

Authors:  Xiaochen Sun; Chenxi Zhang; Huan Guo; Jiao Chen; Yali Tao; Fuxiao Wang; Xixi Lin; Qian Liu; Li Su; An Qin
Journal:  Front Pharmacol       Date:  2020-03-27       Impact factor: 5.810

8.  Oestrogen-activated autophagy has a negative effect on the anti-osteoclastogenic function of oestrogen.

Authors:  Liang Cheng; Yunrong Zhu; Dianshan Ke; Denghui Xie
Journal:  Cell Prolif       Date:  2020-03-11       Impact factor: 6.831

9.  Monitoring Salivary Levels of Interleukin 1 Beta (IL-1β) and Vascular Endothelial Growth Factor (VEGF) for Two Years of Orthodontic Treatment: A Prospective Pilot Study.

Authors:  Hülya Çevik-Aras; Fadimana Isik-Altun; Hatice Kilic-Tok; Julia Naoumova
Journal:  Mediators Inflamm       Date:  2021-05-24       Impact factor: 4.711
  9 in total

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