Literature DB >> 17908551

Silencing insulin resistance through SIRT1.

Janice M Zabolotny1, Young-Bum Kim.   

Abstract

Insulin resistance is an important risk factor for the development of type 2 diabetes and the metabolic syndrome. A new study in this issue of Cell Metabolism (Sun et al., 2007) shows that SIRT1, a mammalian sirtuin homolog and histone deacetylase, can ameliorate insulin resistance by silencing expression of protein tyrosine phosphatase 1B, a major negative regulator of insulin action.

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Year:  2007        PMID： 17908551     DOI： 10.1016/j.cmet.2007.09.004

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  8 in total

Review 1.  Intermittent Fasting to the Eye: A New Dimension Involved in Physiological and Pathological Changes.

Authors:  Jiaqing Feng; Shijiao Zhang; Wenning Li; Tianle Bai; Yulin Liu; Xingyu Chang
Journal:  Front Med (Lausanne)       Date:  2022-05-24

2.  Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B.

Authors:  Balachandar Venkatesan; Nandini Ghosh-Choudhury; Falguni Das; Lenin Mahimainathan; Amrita Kamat; Balakuntalam S Kasinath; Hanna E Abboud; Goutam Ghosh Choudhury
Journal:  FASEB J       Date:  2008-06-20       Impact factor: 5.191

3.  Inhibition of transcriptional activity of c-JUN by SIRT1.

Authors:  Zhanguo Gao; Jianping Ye
Journal:  Biochem Biophys Res Commun       Date:  2008-09-26       Impact factor: 3.575

4.  Inhibition of tumor necrosis factor-α enhanced the antifibrotic effect of empagliflozin in an animal model with renal insulin resistance.

Authors:  Hoda E Mohamed; Mervat E Asker; Mohammed M Keshawy; Rehab A Hasan; Yasmin K Mahmoud
Journal:  Mol Cell Biochem       Date:  2020-01-13       Impact factor: 3.842

5.  Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction.

Authors:  Sandra S Hammer; Cristiano P Vieira; Delaney McFarland; Maximilian Sandler; Yan Levitsky; Tim F Dorweiler; Todd A Lydic; Bright Asare-Bediako; Yvonne Adu-Agyeiwaah; Micheli S Sielski; Mariana Dupont; Ana Leda Longhini; Sergio Li Calzi; Dibyendu Chakraborty; Gail M Seigel; Denis A Proshlyakov; Maria B Grant; Julia V Busik
Journal:  Diabetologia       Date:  2021-03-26       Impact factor: 10.460

6.  Resveratrol attenuates intermittent hypoxia-induced insulin resistance in rats: involvement of Sirtuin 1 and the phosphatidylinositol-4,5-bisphosphate 3-kinase/AKT pathway.

Authors:  Qiuyan Wang; Xiaohui Sun; Xiaobin Li; Xiang Dong; Peng Li; Li Zhao
Journal:  Mol Med Rep       Date:  2014-10-23       Impact factor: 2.952

7.  The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor.

Authors:  Sandra S Hammer; Eleni Beli; Nermin Kady; Qi Wang; Kiana Wood; Todd A Lydic; Goldis Malek; Daniel R Saban; Xiaoxin X Wang; Sugata Hazra; Moshe Levi; Julia V Busik; Maria B Grant
Journal:  EBioMedicine       Date:  2017-07-11       Impact factor: 8.143

8.  Nicotinamide Mononucleotide Is Safely Metabolized and Significantly Reduces Blood Triglyceride Levels in Healthy Individuals.

Authors:  Shintarou Kimura; Misa Ichikawa; Suzuka Sugawara; Tomoko Katagiri; Yuumi Hirasawa; Takahiro Ishikawa; Wataru Matsunaga; Akinobu Gotoh
Journal:  Cureus       Date:  2022-09-05
  8 in total

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