OBJECTIVE: To evaluate the frequency of the real association between paracoccidioidomycosis (PCM) and tuberculosis (TB) as well as the rate of previous TB misdiagnosis in individuals with PCM among the patients treated in the Pulmonology Division of the State University of Campinas Hospital das Clínicas, Campinas, Brazil. METHODS: A retrospective study of 227 adult patients with PCM (chronic form) treated between 1980 and 2005. RESULTS: Of the 227 patients studied, 36 (15.8%) had been previously treated for TB. However, only 18 (7.9%) presented positive sputum smear microscopy results. The remaining 18 (7.9%) neither presented positive sputum smear microscopy nor showed improvement after receiving specific anti-TB treatment. CONCLUSION: Although the existence of an association between PCM and TB has been documented in the literature, misdiagnosis is common due to the superimposition of and the similarity between their clinical and radiographic presentations, thereby warranting the need for bacteriological diagnosis before initiating specific treatment.
OBJECTIVE: To evaluate the frequency of the real association between paracoccidioidomycosis (PCM) and tuberculosis (TB) as well as the rate of previous TB misdiagnosis in individuals with PCM among the patients treated in the Pulmonology Division of the State University of Campinas Hospital das Clínicas, Campinas, Brazil. METHODS: A retrospective study of 227 adult patients with PCM (chronic form) treated between 1980 and 2005. RESULTS: Of the 227 patients studied, 36 (15.8%) had been previously treated for TB. However, only 18 (7.9%) presented positive sputum smear microscopy results. The remaining 18 (7.9%) neither presented positive sputum smear microscopy nor showed improvement after receiving specific anti-TB treatment. CONCLUSION: Although the existence of an association between PCM and TB has been documented in the literature, misdiagnosis is common due to the superimposition of and the similarity between their clinical and radiographic presentations, thereby warranting the need for bacteriological diagnosis before initiating specific treatment.
Authors: Renato do Prado Gomes Pedreira; Eduardo Pereira Guimarães; Marina Lara de Carli; Evandro Monteiro de Sá Magalhães; Alessandro Antônio Costa Pereira; João Adolfo Costa Hanemann Journal: Mycopathologia Date: 2014-04-10 Impact factor: 2.574
Authors: Maria Ângela B Trindade; Denise Miyamoto; Gil Benard; Neusa Y Sakai-Valente; Dewton de M Vasconcelos; Bernard Naafs Journal: Am J Trop Med Hyg Date: 2012-12-03 Impact factor: 2.345
Authors: Gernot Wagner; Deddo Moertl; Axel Eckhardt; Ulrich Sagel; Friedrich Wrba; Karl Dam; Birgit Willinger Journal: Med Mycol Case Rep Date: 2016-12-02
Authors: Larissa Rodrigues Fabris; Úrsulla Vilella Andrade; Aline Ferreira Dos Santos; Ana Paula da Costa Marques; Sandra Maria do Valle Leone de Oliveira; Rinaldo Pôncio Mendes; Anamaria Mello Miranda Paniago Journal: Rev Inst Med Trop Sao Paulo Date: 2014 Mar-Apr Impact factor: 1.846