Literature DB >> 17905884

Nisin-controlled extracellular production of interleukin-2 in Lactococcus lactis strains, without the requirement for a signal peptide sequence.

Antonio Fernández1, Juan M Rodríguez, Roy J Bongaerts, Michael J Gasson, Nikki Horn.   

Abstract

Secretion of the cytokine interleukin-2 (IL-2) was investigated in Lactococcus lactis using the secretory machinery of the bacteriocin lactococcin A. Surprisingly, the lcnCD transport genes were not essential for mouse IL-2 secretion. Furthermore, expression of a mature mouse IL-2 gene resulted in interleukin secretion without the requirement for a leader sequence.

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Year:  2007        PMID： 17905884      PMCID： PMC2168050          DOI： 10.1128/AEM.01247-07

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  23 in total

1.  Nisin biosynthesis genes are encoded by a novel conjugative transposon.

Authors:  N Horn; S Swindell; H Dodd; M Gasson
Journal:  Mol Gen Genet       Date:  1991-08

2.  Gene cloning and expression and secretion of Listeria monocytogenes bacteriophage-lytic enzymes in Lactococcus lactis.

Authors:  S Gaeng; S Scherer; H Neve; M J Loessner
Journal:  Appl Environ Microbiol       Date:  2000-07       Impact factor: 4.792

3.  Introduction of peptidase genes from Lactobacillus delbrueckii subsp. lactis into Lactococcus lactis and controlled expression.

Authors:  U Wegmann; J R Klein; I Drumm; O P Kuipers; B Henrich
Journal:  Appl Environ Microbiol       Date:  1999-11       Impact factor: 4.792

4.  Analysis of the genetic determinant for production of the peptide antibiotic nisin.

Authors:  H M Dodd; N Horn; M J Gasson
Journal:  J Gen Microbiol       Date:  1990-03

5.  T cell growth factor: parameters of production and a quantitative microassay for activity.

Authors:  S Gillis; M M Ferm; W Ou; K A Smith
Journal:  J Immunol       Date:  1978-06       Impact factor: 5.422

6.  Bovine rotavirus nonstructural protein 4 produced by Lactococcus lactis is antigenic and immunogenic.

Authors:  V Enouf; P Langella; J Commissaire; J Cohen; G Corthier
Journal:  Appl Environ Microbiol       Date:  2001-04       Impact factor: 4.792

7.  Purificationa and properties of a fructose-1,6-diphosphate-activated lactate dehydrogenase from Streptococcus faecalis.

Authors:  C L Wittenberger; N Angelo
Journal:  J Bacteriol       Date:  1970-03       Impact factor: 3.490

8.  The leader peptide of colicin V shares consensus sequences with leader peptides that are common among peptide bacteriocins produced by gram-positive bacteria.

Authors:  L S Håvarstein; H Holo; I F Nes
Journal:  Microbiology (Reading)       Date:  1994-09       Impact factor: 2.777

9.  Chronic intake of a marginally low copper diet impairs in vitro activities of lymphocytes and neutrophils from male rats despite minimal impact on conventional indicators of copper status.

Authors:  R G Hopkins; M L Failla
Journal:  J Nutr       Date:  1995-10       Impact factor: 4.798

10.  Heterologous expression of the lactacin F peptides by Carnobacterium piscicola LV17.

Authors:  G E Allison; R W Worobo; M E Stiles; T R Klaenhammer
Journal:  Appl Environ Microbiol       Date:  1995-04       Impact factor: 4.792
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  4 in total

1.  Controlled release of protein from viable Lactococcus lactis cells.

Authors:  Régis Stentz; Roy J Bongaerts; A Patrick Gunning; Mike Gasson; Claire Shearman
Journal:  Appl Environ Microbiol       Date:  2010-03-12       Impact factor: 4.792

2.  Enhanced secretion of biologically active murine interleukin-12 by Lactococcus lactis.

Authors:  Antonio Fernandez; Nikki Horn; Udo Wegmann; Claudio Nicoletti; Michael J Gasson; Arjan Narbad
Journal:  Appl Environ Microbiol       Date:  2008-12-05       Impact factor: 4.792

3.  Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice.

Authors:  Fu Namai; Suguru Shigemori; Tasuku Ogita; Takashi Sato; Takeshi Shimosato
Journal:  Exp Mol Med       Date:  2020-09-28       Impact factor: 8.718

Review 4.  Bacterial Natural Compounds with Anti-Inflammatory and Immunomodulatory Properties (Mini Review).

Authors:  Anahita Jenab; Rasoul Roghanian; Giti Emtiazi
Journal:  Drug Des Devel Ther       Date:  2020-09-18       Impact factor: 4.162
  4 in total

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