Literature DB >> 17905632

Extraosseous epidural multiple myeloma presenting with thoracic spine compression.

Naama Okacha1, Elasri Chrif, Elmostarchid Brahim, Akhaddar Ali, Elbouzidi Abderrahman, Miloudi Gazzaz, Belhachmi Adil, Kadiri Bouchaib, Boucetta Mohamed.   

Abstract

Multiple myeloma is a hematopoetic disorder and multicentric disease, with the most common localisation being the spine. A 47-year-old male presented with progressive paraplegia, superficial and deep sensory disturbance below the level of T4. Spinal magnetic resonance image showed an epidural mass compressing the spinal cord at the level of T4-T6 with intact bone structure. The patient underwent surgical T4-T6 posterior spinal decompression. Microscopic examination and immunohistochemical studies confirmed the diagnosis of multiple myeloma of kappa subtype. Immunoelectrophoresis revealed the presence of immunoglobulin G kappa. The patient was subsequently started on steroids and chemotherapy for myeloma. Extraosseous epidural tumors causing compression myelopathy without evidence of destruction or collapse of vertebral bodies are relatively rare; to our knowledge only four cases have been reported in English literature.

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Year:  2007        PMID: 17905632     DOI: 10.1016/j.jbspin.2007.01.044

Source DB:  PubMed          Journal:  Joint Bone Spine        ISSN: 1297-319X            Impact factor:   4.929


  6 in total

1.  Successful bortezomib treatment in combination with dexamethasone and thalidomide for previously untreated epidural plasmacytoma.

Authors:  Zhiyong Zeng; Ling Zheng; Junfang Lin; Junmin Chen
Journal:  Oncol Lett       Date:  2011-12-28       Impact factor: 2.967

Review 2.  Solitary spinal extradural plasmacytoma: a case report and literature review.

Authors:  S Tsutsumi; Y Yasumoto; M Ito
Journal:  Clin Neuroradiol       Date:  2012-06-16       Impact factor: 3.649

Review 3.  Multiple myeloma.

Authors:  Conor D Collins
Journal:  Cancer Imaging       Date:  2010-02-11       Impact factor: 3.909

4.  Solitary extramedullary plasmacytoma of thoracic epidural space presenting with dorsal compressive myelopathy: A case report and review of literature.

Authors:  Amandeep Kumar; Guru Dutt Satyarthee; Mukund Sable; Vaishali Suri; Bhawani S Sharma
Journal:  J Neurosci Rural Pract       Date:  2015 Jul-Sep

5.  Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective.

Authors:  Kee-Yong Ha; Young-Hoon Kim; Hyun-Woo Kim
Journal:  J Korean Neurosurg Soc       Date:  2013-08-31

6.  Multiple myeloma with intracranial and spinal intradural metastasis: A case report.

Authors:  Wei-Lin Hsu; Jeng-Hung Guo; Ying-Ying Hung; Der-Yang Cho; Der-Cherng Chen
Journal:  Biomedicine (Taipei)       Date:  2020-09-01
  6 in total

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