| Literature DB >> 17905535 |
J-P Lavigne1, G Bourg, H Botto, A Sotto.
Abstract
Cranberries (Vaccinium macrocarpon) have long been the focus of interest for their beneficial effects in preventing urinary tract infections. Among cranberry compounds, a group of proanthocyanidins (PACs) with A-type linkages were isolated which exhibit bacterial anti-adhesion activity against uropathogenic Escherichia coli strains. These PAC inhibit P-fimbriae synthesis and induce a bacterial deformation. This activity was demonstrated on both antibiotic susceptible and resistant bacteria. This review focused on the last discoveries in the knowledge of cranberry effects.Entities:
Mesh：
Substances：
Year: 2007 PMID： 17905535 DOI： 10.1016/j.patbio.2007.07.005
Source DB: PubMed Journal: Pathol Biol (Paris) ISSN： 0369-8114