Literature DB >> 17905316

Clinical outcomes in older patients after posterolateral lumbar fusion.

Steven D Glassman1, Leah Y Carreon, John R Dimar, Mitchell J Campbell, Rolando M Puno, John R Johnson.   

Abstract

BACKGROUND CONTEXT: Older patients are often advised that their age is a contraindication to lumbar fusion surgery. There is, however, limited available data to support or contradict this assertion. Although prior studies of surgical treatment for lumbar degenerative disease suggest that older patients obtain symptomatic pain relief, an evaluation of fusion outcomes based on modern Health-Related Quality of Life (HRQOL) measures is lacking.
PURPOSE: The purpose of this study was to document clinical outcomes based on standardized HRQOL measures in patients over 65 years of age treated by lumbar decompression and fusion surgery. DESIGN/
SETTING: This study was a retrospective review of prospectively collected patient reported outcomes data. PATIENT SAMPLE: Ninety-seven consecutive patients over 65 years of age treated by lumbar decompression and fusion between 2000 and 2004 were enrolled in a prospective health status outcomes protocol. Eighty-five patients (88%) had complete data at a minimum 2-year follow-up. OUTCOME MEASURES: Medical Outcomes Study Short Form 36v.2 (SF-36), Oswestry Disability Index (ODI), numeric rating scales (NRS) back and leg pain scores.
METHODS: Patients over 65 years of age treated by lumbar fusion were evaluated based on HRQOL measures at a minimum of 2 years postoperatively. Variables including history of prior surgery and occurrence of a perioperative complication were evaluated. A comparison group of patients 50 to 64 years of age was also analyzed.
RESULTS: In patients over 65 years old, mean improvement of 6.21 points in SF-36 Physical Composite Score and 5.75 points in SF-36 Mental Composite Score was observed. There was a mean 16.38-point improvement in ODI, 3.08-point improvement in back pain NRS, and 2.65-point improvement in leg pain NRS. SF-36 subscale scores showed improvement for all parameters except general health, where there was a small but statistically significant decline. There was no difference in outcomes at 2 years postoperatively based on the occurrence of a perioperative complication. Patients undergoing a primary lumbar surgical procedure had consistently better outcomes than patients undergoing a revision procedure.
CONCLUSIONS: The results of this study support the efficacy of lumbar decompression and fusion in selected patients over 65 years of age. Occurrence of a perioperative complication did not adversely affect clinical outcome. Patients undergoing a revision procedure should be counseled with regard to the more limited benefits seen with revision surgery.

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Year:  2007        PMID: 17905316     DOI: 10.1016/j.spinee.2006.11.003

Source DB:  PubMed          Journal:  Spine J        ISSN: 1529-9430            Impact factor:   4.166


  20 in total

1.  The efficacy of rhBMP-2 versus autograft for posterolateral lumbar spine fusion in elderly patients.

Authors:  Kwang-Bok Lee; Cyrus E Taghavi; Margaret S Hsu; Kyung-Jin Song; Jeong Hyun Yoo; Gun Keorochana; Stephanie S Ngo; Jeffrey C Wang
Journal:  Eur Spine J       Date:  2009-12-30       Impact factor: 3.134

2.  Should age be a contraindication for degenerative lumbar surgery?

Authors:  Daniel Pérez-Prieto; Carlos Lozano-Álvarez; Guillem Saló; Antoni Molina; Andreu Lladó; Lluís Puig-Verdié; Manuel Ramírez-Valencia
Journal:  Eur Spine J       Date:  2014-01-24       Impact factor: 3.134

3.  Trends analysis of rhBMP utilization in single-level posterior lumbar fusion (PLF) in the United States.

Authors:  Lifeng Lao; Jeremiah R Cohen; Elizabeth L Lord; Zorica Buser; Jeffrey C Wang
Journal:  Eur Spine J       Date:  2015-05-24       Impact factor: 3.134

4.  Instrumented fusion surgery in elderly patients (over 75 years old): clinical and radiological results in a series of 53 patients.

Authors:  Francesco Costa; Alessandro Ortolina; Massimo Tomei; Andrea Cardia; Edwin Zekay; Maurizio Fornari
Journal:  Eur Spine J       Date:  2013-09-20       Impact factor: 3.134

5.  The immense heterogeneity of frailty in neurosurgery: a systematic literature review.

Authors:  Julia Pazniokas; Chirag Gandhi; Brianna Theriault; Meic Schmidt; Chad Cole; Fawaz Al-Mufti; Justin Santarelli; Christian A Bowers
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6.  Revision surgery following operations for lumbar stenosis.

Authors:  Richard A Deyo; Brook I Martin; William Kreuter; Jeffrey G Jarvik; Heather Angier; Sohail K Mirza
Journal:  J Bone Joint Surg Am       Date:  2011-11-02       Impact factor: 5.284

7.  Trends, major medical complications, and charges associated with surgery for lumbar spinal stenosis in older adults.

Authors:  Richard A Deyo; Sohail K Mirza; Brook I Martin; William Kreuter; David C Goodman; Jeffrey G Jarvik
Journal:  JAMA       Date:  2010-04-07       Impact factor: 56.272

8.  Outcomes of Instrumented Posterolateral Fusion for Patients Over 70 Years with Degenerative Lumbar Spinal Disease: A Minimum of 2 Years Follow-up.

Authors:  Mong Lee; Hee-Jin Yang; Sang Hyung Lee; Sung Bae Park
Journal:  Korean J Spine       Date:  2012-06-30

9.  Instrumented intervertebral or posterolateral fusion in elderly patients: clinical results of a single center.

Authors:  Stefan Endres; Rene Aigner; Axel Wilke
Journal:  BMC Musculoskelet Disord       Date:  2011-08-18       Impact factor: 2.362

10.  Impact of instrumentation in lumbar spinal fusion in elderly patients: 71 patients followed for 2-7 years.

Authors:  Thomas Andersen; Finn B Christensen; Bent Niedermann; Peter Helmig; Kristian Høy; Ebbe S Hansen; Cody Bünger
Journal:  Acta Orthop       Date:  2009-08       Impact factor: 3.717

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