Literature DB >> 17904888

Signalling pathways mediating type I interferon gene expression.

Michael R Edwards1, Louise Slater, Sebastian L Johnston.   

Abstract

Type I interferon-alpha/beta play an essential role in immunity to viruses. While interferon-beta has been used as a model of a complex promoter, many of the signalling pathways leading to interferon-beta gene expression remain controversial. Recent milestones include the discovery of Toll-like receptors and RNA helicases that signal via a novel kinase complex composed of I kappa B kinase-iota/epsilon or TANK binding kinase-1. This review provides a timely summary of this rapidly expanding field, focusing specifically on the various viral RNA binding molecules and their associated signalling pathways.

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Year:  2007        PMID: 17904888     DOI: 10.1016/j.micinf.2007.06.008

Source DB:  PubMed          Journal:  Microbes Infect        ISSN: 1286-4579            Impact factor:   2.700


  14 in total

1.  Type I Interferon Regulates the Placental Inflammatory Response to Bacteria and is Targeted by Virus: Mechanism of Polymicrobial Infection-Induced Preterm Birth.

Authors:  Karen Racicot; Ja Young Kwon; Paulomi Aldo; Vikki Abrahams; Ayman El-Guindy; Roberto Romero; Gil Mor
Journal:  Am J Reprod Immunol       Date:  2016-02-19       Impact factor: 3.886

2.  IFN-α mediates the development of autoimmunity both by direct tissue toxicity and through immune cell recruitment mechanisms.

Authors:  Nagako Akeno; Eric P Smith; Mihaela Stefan; Amanda K Huber; Weijia Zhang; Mehdi Keddache; Yaron Tomer
Journal:  J Immunol       Date:  2011-03-14       Impact factor: 5.422

3.  Viral respiratory infection and the link to asthma.

Authors:  James E Gern
Journal:  Pediatr Infect Dis J       Date:  2008-10       Impact factor: 2.129

Review 4.  Rhinovirus and the initiation of asthma.

Authors:  James E Gern
Journal:  Curr Opin Allergy Clin Immunol       Date:  2009-02

5.  Nucleotide receptor P2RX7 stimulation enhances LPS-induced interferon-β production in murine macrophages.

Authors:  M L Gavala; Y-P Liu; L Y Lenertz; L Zeng; J B Blanchette; A G Guadarrama; L C Denlinger; P J Bertics; J A Smith
Journal:  J Leukoc Biol       Date:  2013-08-02       Impact factor: 4.962

6.  Interactions between the influenza A virus RNA polymerase components and retinoic acid-inducible gene I.

Authors:  Weizhong Li; Hongjun Chen; Troy Sutton; Adebimpe Obadan; Daniel R Perez
Journal:  J Virol       Date:  2014-06-18       Impact factor: 5.103

7.  Toll-like receptor 3 has a protective role against West Nile virus infection.

Authors:  Stephane Daffis; Melanie A Samuel; Mehul S Suthar; Michael Gale; Michael S Diamond
Journal:  J Virol       Date:  2008-08-20       Impact factor: 5.103

8.  Inability of NS1 protein from an H5N1 influenza virus to activate PI3K/Akt signaling pathway correlates to the enhanced virus replication upon PI3K inhibition.

Authors:  Weizhong Li; Gefei Wang; Heng Zhang; Yanqin Shen; Jianping Dai; Liqi Wu; Jianxiang Zhou; Zhiwu Jiang; Kangsheng Li
Journal:  Vet Res       Date:  2012-04-24       Impact factor: 3.683

Review 9.  Interplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virus.

Authors:  Yan Sun; Mingyuan Han; Chiyong Kim; Jay G Calvert; Dongwan Yoo
Journal:  Viruses       Date:  2012-04-02       Impact factor: 5.048

10.  Reduced sputum expression of interferon-stimulated genes in severe COPD.

Authors:  Clarissa Hilzendeger; Jane da Silva; Monique Henket; Florence Schleich; Jean Louis Corhay; Tatiana Kebadze; Michael R Edwards; Patrick Mallia; Sebastian L Johnston; Renaud Louis
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2016-06-30
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