| Literature DB >> 17904882 |
Enrico P Spugnini1, Bruno Vincenzi, Gennaro Citro, Giuseppe Tonini, Ivan Dotsinsky, Nikolay Mudrov, Alfonso Baldi.
Abstract
Squamous cell carcinomas (SCC) of the skin are commonly described in cats. Reported treatments include surgery, radiation therapy and photodynamic therapy. This preliminary study reports on the management of these lesions combining the local administration of bleomycin (plus hyaluronidase for a more uniform distribution) with permeabilizing biphasic electric pulses. Nine cats with SCC graded T(2)-T(4) were treated over a 5 year period, and each cat received two sessions of electrochemotherapy (ECT) 1 week apart. The side effects of this treatment were minimal and limited to mild erythema of the nose. Seven of the cats (77.7%) had a complete response lasting up to 3 years. ECT seems to be a safe and effective option for the treatment of feline sun-induced squamous cell carcinomas and warrants further investigation.Entities:
Mesh：
Year: 2007 PMID： 17904882 DOI： 10.1016/j.tvjl.2007.08.011
Source DB: PubMed Journal: Vet J ISSN： 1090-0233 Impact factor: 2.688