INTRODUCTION: Microhemorrhages seen on gradient-echo magnetic resonance imaging are thought to be a manifestation of small-vessel disease. It was the aim of our study to evaluate the prevalence of microhemorrhage for patients presenting with acute lacunar infarction. METHODS: We obtained gradient-echo and diffusion-weighted magnetic resonance imaging as part of the acute stroke workup in 46 patients presenting with lacunar infarction. RESULTS: Gradient-echo magnetic resonance imaging was abnormal in 24 of 46 (52%) patients. Microhemorrhage was seen in 21 patients (46%), 2 patients had multiple microhemorrhages and a frank hemorrhage, and 3 patients had frank hemorrhage in the absence of microhemorrhage. Prior symptomatic stroke was the only significant risk factor for the presence of microhemorrhages. CONCLUSION: Microhemorrhages are present in approximately half of patients with lacunar infarcts and appear to be a marker of severity of small-vessel disease.
INTRODUCTION: Microhemorrhages seen on gradient-echo magnetic resonance imaging are thought to be a manifestation of small-vessel disease. It was the aim of our study to evaluate the prevalence of microhemorrhage for patients presenting with acute lacunar infarction. METHODS: We obtained gradient-echo and diffusion-weighted magnetic resonance imaging as part of the acute stroke workup in 46 patients presenting with lacunar infarction. RESULTS: Gradient-echo magnetic resonance imaging was abnormal in 24 of 46 (52%) patients. Microhemorrhage was seen in 21 patients (46%), 2 patients had multiple microhemorrhages and a frank hemorrhage, and 3 patients had frank hemorrhage in the absence of microhemorrhage. Prior symptomatic stroke was the only significant risk factor for the presence of microhemorrhages. CONCLUSION: Microhemorrhages are present in approximately half of patients with lacunar infarcts and appear to be a marker of severity of small-vessel disease.
Authors: Ashkan Shoamanesh; Lesly A Pearce; Carlos Bazan; Luciana Catanese; Leslie A McClure; Mukul Sharma; Joan Marti-Fabregas; David C Anderson; Carlos S Kase; Robert G Hart; Oscar R Benavente Journal: Ann Neurol Date: 2017-07-19 Impact factor: 10.422
Authors: A Hess; I Klein; B Iung; P Lavallée; E Ilic-Habensus; Q Dornic; F Arnoult; L Mimoun; M Wolff; X Duval; J-P Laissy Journal: AJNR Am J Neuroradiol Date: 2013-05-02 Impact factor: 3.825
Authors: Paul A Yates; Victor L Villemagne; Kathryn A Ellis; Patricia M Desmond; Colin L Masters; Christopher C Rowe Journal: Front Neurol Date: 2014-01-06 Impact factor: 4.003
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