Literature DB >> 17903574

Laryngeal tuberculosis: a review of 26 cases.

Chen-Chi Wang1, Chang-Chun Lin, Ching-Ping Wang, Shih-An Liu, Rong-San Jiang.   

Abstract

OBJECTIVES: To review the clinical characteristics of laryngeal tuberculosis. STUDY
DESIGN: Retrospective case series. SUBJECTS AND METHODS: Medical records of 26 histopathology-confirmed cases in a tertiary medical center from 1992 to 2006.
RESULTS: The female patients were significantly younger than male patients. Hoarseness is the most common symptom (84.6%) because true vocal fold is most commonly involved (80.8%). Infection usually involves unilateral (66.7%) and right-side larynx but multiple subsites of the larynx (57.7%). The appearance of the affected larynx may have mixed features and change before diagnosis. Laryngeal tuberculosis is usually misdiagnosed as laryngeal cancer, especially in patients with malignant signs such as enlarged cervical lymph nodes and vocal fold immobility. Chest film is better than sputum examinations for screening.
CONCLUSION: We should be especially alert about TB infection when facing young female patients with unusual laryngeal lesions. Extensive laser excision before diagnosis should be avoided because after antituberculous treatment, prognosis is usually good and vocal fold immobility could be reversible.

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Mesh:

Year:  2007        PMID: 17903574     DOI: 10.1016/j.otohns.2007.04.002

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


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