Literature DB >> 17903506

Aortic root remodeling: ten-year experience with 274 patients.

Diana Aicher1, Frank Langer, Henning Lausberg, Benjamin Bierbach, Hans-Joachim Schäfers.   

Abstract

OBJECTIVES: Dilatation of the aortic root with concomitant aortic regurgitation can be treated by valve-preserving surgery. We have consistently chosen root remodeling rather than reimplantation whenever the aortoventricular junction was not dilated. We have analyzed our 11-year experience with root remodeling.
METHODS: Between October 1995 and October 2006, 274 patients (201 male; 73 female, aged 59 +/- 15 years) were treated by root remodeling in the presence of a preserved aortoventricular diameter (<30 mm). Acute aortic dissection was present in 46 patients. The valve anatomy was tricuspid in 193 and bicuspid in 81 patients. Cusp disease was additionally corrected in 173 (63%) patients. Follow-up was complete in 99%. Cumulative follow-up was 1045 patient-years (mean of 4.0 +/- 2.7 years).
RESULTS: Hospital mortality was 3.6% (elective 3.1%; emergency 6.5%). One patient had endocarditis 2 months postoperatively and subsequently underwent valve replacement. Freedom from aortic regurgitation of grade II or more was 91% and 87% at 10 years for bicuspid and tricuspid aortic valves. Nine patients required reoperation: in 6 patients the valve was replaced and in 3 patients rerepaired. Freedom from reoperation was 96% at 5 and 10 years, and freedom from valve replacement was 98% at 5 and 10 years. A comparison of 3 operative periods (1995-1998, 1999-2002, and 2003-2006) showed that with increasing experience cusp prolapse was diagnosed and corrected more frequently (8/49 = 17%; 62/105 = 59%; 103/108 = 82%; P < .0001), and repair stability significantly improved over time (P = .007).
CONCLUSIONS: Root remodeling leads to durable restoration of aortic valve function in both tricuspid and bicuspid valve anatomy. Aggressive correction of cusp prolapse seems to have a beneficial effect on aortic valve competence.

Entities:  

Mesh:

Year:  2007        PMID: 17903506     DOI: 10.1016/j.jtcvs.2007.05.052

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  17 in total

Review 1.  Snake venom thrombin-like enzymes: from reptilase to now.

Authors:  H C Castro; R B Zingali; M G Albuquerque; M Pujol-Luz; C R Rodrigues
Journal:  Cell Mol Life Sci       Date:  2004-04       Impact factor: 9.261

2.  Complications after aortic valve repair and valve-sparing procedures.

Authors:  Michel Van Dyck; David Glineur; Laurent de Kerchove; Gébrine El Khoury
Journal:  Ann Cardiothorac Surg       Date:  2013-01

3.  Anatomy and pathophysiology of the ventriculo-aortic junction: implication in aortic valve repair surgery.

Authors:  Laurent de Kerchove; Gebrine El Khoury
Journal:  Ann Cardiothorac Surg       Date:  2013-01

4.  Partial root remodeling on the two sinuses for acute type a aortic dissection with right coronary arterial dissection.

Authors:  Akira Katayama; Naomichi Uchida; Miwa Sutoh; Taijiro Sueda
Journal:  Ann Vasc Dis       Date:  2013-09-05

5.  Valve-sparing aortic root replacement and tricuspidization in a patient with an asymmetric bicuspid aortic valve.

Authors:  Igor E Konstantinov; Pankaj Saxena
Journal:  Tex Heart Inst J       Date:  2010

6.  PRO-CON debate: valve sparing aortic root surgery. PRO: reimplantation.

Authors:  Ruggero De Paulis
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-10-10

7.  Surgical Approaches to Aortic Valve Replacement and Repair-Insights and Challenges.

Authors:  Basel Ramlawi; Mahesh Ramchandani; Michael J Reardon
Journal:  Interv Cardiol       Date:  2014-03

Review 8.  A measured approach to managing the aortic root in patients with bicuspid aortic valve disease.

Authors:  Ismail El-Hamamsy; Magdi H Yacoub
Journal:  Curr Cardiol Rep       Date:  2009-03       Impact factor: 2.931

9.  Aortic valve sparing operations: a review.

Authors:  Tirone E David
Journal:  Korean J Thorac Cardiovasc Surg       Date:  2012-08-03

Review 10.  Surgical treatment of aortic valve disease.

Authors:  Tirone E David
Journal:  Nat Rev Cardiol       Date:  2013-05-14       Impact factor: 32.419

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.