Literature DB >> 17901873

MALDI imaging mass spectrometry: molecular snapshots of biochemical systems.

Dale S Cornett1, Michelle L Reyzer, Pierre Chaurand, Richard M Caprioli.   

Abstract

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is emerging as a powerful tool for investigating the distribution of molecules within biological systems through the direct analysis of thin tissue sections. Unique among imaging methods, MALDI-IMS can determine the distribution of hundreds of unknown compounds in a single measurement. We discuss the current state of the art of MALDI-IMS along with some recent applications and technological developments that illustrate not only its current capabilities but also the future potential of the technique to provide a better understanding of the underlying molecular mechanisms of biological processes.

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Year:  2007        PMID： 17901873     DOI： 10.1038/nmeth1094

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  240 in total

1.  Three-dimensional imaging of lipids and metabolites in tissues by nanospray desorption electrospray ionization mass spectrometry.

Authors:  Ingela Lanekoff; Kristin Burnum-Johnson; Mathew Thomas; Jeeyeon Cha; Sudhansu K Dey; Pengxiang Yang; Maria C Prieto Conaway; Julia Laskin
Journal:  Anal Bioanal Chem       Date:  2014-11-14       Impact factor: 4.142

Review 2.  Stable isotope-resolved metabolomics and applications for drug development.

Authors:  Teresa W-M Fan; Pawel K Lorkiewicz; Katherine Sellers; Hunter N B Moseley; Richard M Higashi; Andrew N Lane
Journal:  Pharmacol Ther       Date:  2011-12-23       Impact factor: 12.310

Review 3.  Changing environments and structure--property relationships in marine biomaterials.

Authors:  J Herbert Waite; Christopher C Broomell
Journal:  J Exp Biol       Date:  2012-03-15       Impact factor: 3.312

Review 4.  Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.

Authors:  Alfred H Merrill
Journal:  Chem Rev       Date:  2011-09-26       Impact factor: 60.622

5.  Digital imaging mass spectrometry.

Authors:  Casimir Bamberger; Uwe Renz; Andreas Bamberger
Journal:  J Am Soc Mass Spectrom       Date:  2011-04-12       Impact factor: 3.109

6.  Imaging mass spectrometry data reduction: automated feature identification and extraction.

Authors:  Liam A McDonnell; Alexandra van Remoortere; Nico de Velde; René J M van Zeijl; André M Deelder
Journal:  J Am Soc Mass Spectrom       Date:  2010-08-21       Impact factor: 3.109

7.  Modulation of behavioral networks by selective interneuronal inactivation.

Authors:  M J Schmidt; S Horvath; P Ebert; J L Norris; E H Seeley; J Brown; L Gellert; M Everheart; K A Garbett; T W Grice; R M Caprioli; K Mirnics
Journal:  Mol Psychiatry       Date:  2013-12-10       Impact factor: 15.992

8.  A Simple Sonication Improves Protein Signal in Matrix-Assisted Laser Desorption Ionization Imaging.

Authors:  Li-En Lin; Pin-Rui Su; Hsin-Yi Wu; Cheng-Chih Hsu
Journal:  J Am Soc Mass Spectrom       Date:  2018-02-01       Impact factor: 3.109

9.  High resolution metabolite imaging in the hippocampus following neonatal exposure to the environmental toxin BMAA using ToF-SIMS.

Authors:  Jörg Hanrieder; Lorenz Gerber; Åsa Persson Sandelius; Eva B Brittebo; Andrew G Ewing; Oskar Karlsson
Journal:  ACS Chem Neurosci       Date:  2014-05-09       Impact factor: 4.418

Review 10.  Mass Spectrometry Approaches to Glycomic and Glycoproteomic Analyses.

Authors:  L Renee Ruhaak; Gege Xu; Qiongyu Li; Elisha Goonatilleke; Carlito B Lebrilla
Journal:  Chem Rev       Date:  2018-03-19       Impact factor: 60.622
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