| Literature DB >> 179017 |
Abstract
A cold-sensitive mutant of CHO cells has features of "reverse transformation" at the non-premissive temperature of 33 degrees C. Cells accumulate at G1 with altered morphology and remain viable and quiescent for more than 40 d. Such cultures are synchronised by a temperature shift back to the permissive 39 degrees C.Mesh:
Substances:
Year: 1976 PMID: 179017 DOI: 10.1038/261205a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962