Literature DB >> 17900910

Design of a pyrene-containing fluorescence probe for labeling of RNA poly(A) tracts.

Kazuo Tanaka1, Akimitsu Okamoto.   

Abstract

A labeling probe containing a pyrenecarboxamide-tethered modified DNA base, (Py)U, has been developed for fluorometric detection of RNA poly(A) tracts, in which the fluorescence emission intensity was controlled by the microstructural change around (Py)U caused by binding with the target RNA.

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Year:  2007        PMID: 17900910     DOI: 10.1016/j.bmc.2007.09.024

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

Review 1.  Fluorescent analogs of biomolecular building blocks: design, properties, and applications.

Authors:  Renatus W Sinkeldam; Nicholas J Greco; Yitzhak Tor
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

2.  Highly efficient incorporation of the fluorescent nucleotide analogs tC and tCO by Klenow fragment.

Authors:  Peter Sandin; Gudrun Stengel; Thomas Ljungdahl; Karl Börjesson; Bertil Macao; L Marcus Wilhelmsson
Journal:  Nucleic Acids Res       Date:  2009-04-28       Impact factor: 16.971

  2 in total

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