Literature DB >> 17900195

Novel proton acceptor immonium-type coupling reagents: application in solution and solid-phase peptide synthesis.

Ayman El-Faham1, Fernando Albericio.   

Abstract

A novel proton acceptor coupling reagent shows superiority to those described previously. The oxygen in the carbocation moiety confers more solubility to the reagent. Furthermore, it enhances coupling yields and decreases racemization, allowing the use of 1 equiv of base.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17900195     DOI: 10.1021/ol701817u

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

Review 1.  Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies.

Authors:  Ricardo Ribeiro; Eugénia Pinto; Carla Fernandes; Emília Sousa
Journal:  Mar Drugs       Date:  2022-06-15       Impact factor: 6.085

2.  (E)-Ethyl-2-cyano-2-(((2,4,6-trichlorobenzoyl)oxy)imino)acetate: A Modified Yamaguchi Reagent for Enantioselective Esterification, Thioesterification, Amidation, and Peptide Synthesis.

Authors:  Jyoti Chandra; Srinivasa Rao Manne; Sandip Mondal; Bhubaneswar Mandal
Journal:  ACS Omega       Date:  2018-06-06

3.  Synthesis of 2-(4,6-dimethoxy-1,3,5-triazin-2-yloxyimino) derivatives: application in solution peptide synthesis.

Authors:  Tarfah I Al-Warhi; Hassan M A Al-Hazimi; Ayman El-Faham; Fernando Albericio
Journal:  Molecules       Date:  2010-12-20       Impact factor: 4.411

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.