BACKGROUND/AIMS: 10% of Parkinson's disease (PD) patients have young-onset PD (YOPD). We compared YOPD patients to control patients in terms of hospital utilization and outcomes and medical comorbidities during hospitalization. METHODS: The Nationwide Inpatient Sample (NIS) provides yearly data on hospital admissions and discharges from approximately 1,000 hospitals. NIS data sets (1998-2003) were used to identify persons aged 18-40 years, including 714 PD patients and 2,007 randomly selected control patients (1:3 matching). RESULTS: Hospital length of stay (p < 0.001) and number of discharge diagnoses (p < 0.001) were higher in PD patients than controls. PD patients were more likely than controls to be discharged to a short-term hospital (odds ratio, OR, 2.23, 95% confidence interval, CI, 1.30-3.84, p = 0.004) or a skilled nursing facility (OR 4.14, 95% CI 3.06-5.61, p < 0.001); 20.4% required transfer to a short-term hospital or another facility. The most common discharge Diagnosis-Related Group code in PD patients was psychosis (23% of patients) whereas pneumonia and hip or pelvic fractures were not associated with PD. CONCLUSIONS: YOPD patients had greater healthcare utilization and hospital morbidity than controls. Upon discharge, 1 in 5 required transfer to a short-term hospital or another facility. Psychosis was the most common comorbidity whereas several comorbidities associated with older PD patients were not common. (c) 2007 S. Karger AG, Basel.
BACKGROUND/AIMS: 10% of Parkinson's disease (PD) patients have young-onset PD (YOPD). We compared YOPD patients to control patients in terms of hospital utilization and outcomes and medical comorbidities during hospitalization. METHODS: The Nationwide Inpatient Sample (NIS) provides yearly data on hospital admissions and discharges from approximately 1,000 hospitals. NIS data sets (1998-2003) were used to identify persons aged 18-40 years, including 714 PDpatients and 2,007 randomly selected control patients (1:3 matching). RESULTS: Hospital length of stay (p < 0.001) and number of discharge diagnoses (p < 0.001) were higher in PDpatients than controls. PDpatients were more likely than controls to be discharged to a short-term hospital (odds ratio, OR, 2.23, 95% confidence interval, CI, 1.30-3.84, p = 0.004) or a skilled nursing facility (OR 4.14, 95% CI 3.06-5.61, p < 0.001); 20.4% required transfer to a short-term hospital or another facility. The most common discharge Diagnosis-Related Group code in PDpatients was psychosis (23% of patients) whereas pneumonia and hip or pelvic fractures were not associated with PD. CONCLUSIONS: YOPD patients had greater healthcare utilization and hospital morbidity than controls. Upon discharge, 1 in 5 required transfer to a short-term hospital or another facility. Psychosis was the most common comorbidity whereas several comorbidities associated with older PDpatients were not common. (c) 2007 S. Karger AG, Basel.
Authors: Michael J Aminoff; Chad W Christine; Joseph H Friedman; Kelvin L Chou; Kelly E Lyons; Rajesh Pahwa; Bastian R Bloem; Sotirios A Parashos; Catherine C Price; Irene A Malaty; Robert Iansek; Ivan Bodis-Wollner; Oksana Suchowersky; Wolfgang H Oertel; Jorge Zamudio; Joyce Oberdorf; Peter Schmidt; Michael S Okun Journal: Parkinsonism Relat Disord Date: 2010-12-14 Impact factor: 4.891