Literature DB >> 17896599

Detection and visualization of surface-pockets to enable phenotyping studies.

Kishore Mosaliganti1, Firdaus Janoos, Richard Sharp, Randall Ridgway, Raghu Machiraju, Kun Huang, Pamela Wenzel, Alain deBruin, Gustavo Leone, Joel Saltz.   

Abstract

In this paper, we propose a technique for detecting pockets on a surface-of-interest. A sequence of propagating fronts converging to the target surface is used as the basis for inspection. We compute a correspondence function between the initial and the target surface. This leads to a natural definition of the local feature size measured as the evolution distance between mapped points. Surface pockets are then extracted as salient clusters embedded in the feature space. The level-set initialization also determines the scale-space of the extracted pockets. Results are presented on a case-study in which the focus is to chronicle the phenotyping differences in genetically modified mouse placenta. Our results are validated based on manually verified ground-truth.

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Year:  2007        PMID: 17896599     DOI: 10.1109/TMI.2007.903570

Source DB:  PubMed          Journal:  IEEE Trans Med Imaging        ISSN: 0278-0062            Impact factor:   10.048


  1 in total

1.  An imaging workflow for characterizing phenotypical change in large histological mouse model datasets.

Authors:  Kishore Mosaliganti; Tony Pan; Randall Ridgway; Richard Sharp; Lee Cooper; Alex Gulacy; Ashish Sharma; Okan Irfanoglu; Raghu Machiraju; Tahsin Kurc; Alain de Bruin; Pamela Wenzel; Gustavo Leone; Joel Saltz; Kun Huang
Journal:  J Biomed Inform       Date:  2008-04-07       Impact factor: 6.317

  1 in total

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