M Cristina Leske1. 1. Department of Preventive Medicine, Stony Brook University School of Medicine, Stony Brook, New York 11790-8036, USA. cleske@notes.cc.sunysb.edu
Abstract
PURPOSE: To provide a summary overview of current epidemiologic data on open-angle glaucoma. METHODS: Literature review. RESULTS: The review summarizes information on the following topics: Definition of open-angle glaucoma; Prevalence data from studies conducted in various populations; Incidence data available from population studies; Risk factors, categorized as demographic, familial, systemic, and ocular; and, Progression factors. It concludes by outlining the epidemiologic contributions to glaucoma and suggesting research needs. CONCLUSIONS: Epidemiologic studies have contributed greatly to our knowledge of open-angle glaucoma. Still, many gaps remain, and the multifactorial etiology of glaucoma needs further clarification. Future research would benefit by standardizing the approach to define the disease, thus allowing better comparability across studies. A major priority is to achieve a better understanding of risk factors, which are likely to involve gene-environment interactions.
PURPOSE: To provide a summary overview of current epidemiologic data on open-angle glaucoma. METHODS: Literature review. RESULTS: The review summarizes information on the following topics: Definition of open-angle glaucoma; Prevalence data from studies conducted in various populations; Incidence data available from population studies; Risk factors, categorized as demographic, familial, systemic, and ocular; and, Progression factors. It concludes by outlining the epidemiologic contributions to glaucoma and suggesting research needs. CONCLUSIONS: Epidemiologic studies have contributed greatly to our knowledge of open-angle glaucoma. Still, many gaps remain, and the multifactorial etiology of glaucoma needs further clarification. Future research would benefit by standardizing the approach to define the disease, thus allowing better comparability across studies. A major priority is to achieve a better understanding of risk factors, which are likely to involve gene-environment interactions.
Authors: Michaël J A Girard; Nicholas G Strouthidis; Adrien Desjardins; Jean Martial Mari; C Ross Ethier Journal: J R Soc Interface Date: 2013-07-24 Impact factor: 4.118
Authors: John C Hwang; Ranjith Konduru; Xinbo Zhang; Ou Tan; Brian A Francis; Rohit Varma; Mitra Sehi; David S Greenfield; Srinivas R Sadda; David Huang Journal: Invest Ophthalmol Vis Sci Date: 2012-05-17 Impact factor: 4.799