Literature DB >> 17896033

Organocatalytic asymmetric "anti-Michael" reaction of beta-ketoesters.

José Alemán1, Efraím Reyes, Bo Richter, Jacob Overgaard, Karl Anker Jørgensen.   

Abstract

The first organocatalytic "anti-Michael" reaction of cyclic-beta-ketoesters to unsaturated double bonds is described in a highly asymmetric version leading to the synthesis of alpha,alpha'-disubstituted branched double bonds as optically active Baylis-Hillman-like adducts.

Year:  2007        PMID: 17896033     DOI: 10.1039/b710393j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  tert-Butyl 2-methyl-2-(4-nitro-benzo-yl)propanoate.

Authors:  Chelsey M Crosse; Marshall W Logue; Rudy L Luck; Louis R Pignotti; Melissa F Waineo
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-01-30

2.  Nitro-enabled catalytic enantioselective formal umpolung alkenylation of β-ketoesters.

Authors:  Abhijnan Ray Choudhury; Madhu Sudan Manna; Santanu Mukherjee
Journal:  Chem Sci       Date:  2017-08-02       Impact factor: 9.825

  2 in total

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