Literature DB >> 17893894

Design of beta-hairpin peptidomimetics that inhibit binding of alpha-helical HIV-1 Rev protein to the rev response element RNA.

Kerstin Moehle1, Zafiria Athanassiou, Krystyna Patora, Amy Davidson, Gabriele Varani, John A Robinson.   

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Year:  2007        PMID： 17893894      PMCID： PMC3809837          DOI： 10.1002/anie.200702801

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  17 in total

1.  The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution.

Authors:  J A Ippolito; T A Steitz
Journal:  J Mol Biol       Date:  2000-01-28       Impact factor: 5.469

2.  Structure-guided peptidomimetic design leads to nanomolar beta-hairpin inhibitors of the Tat-TAR interaction of bovine immunodeficiency virus.

Authors:  Zafiria Athanassiou; Krystyna Patora; Ricardo L A Dias; Kerstin Moehle; John A Robinson; Gabriele Varani
Journal:  Biochemistry       Date:  2007-01-23       Impact factor: 3.162

3.  The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA.

Authors:  M H Malim; J Hauber; S Y Le; J V Maizel; B R Cullen
Journal:  Nature       Date:  1989-03-16       Impact factor: 49.962

4.  The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization.

Authors:  M Emerman; R Vazeux; K Peden
Journal:  Cell       Date:  1989-06-30       Impact factor: 41.582

5.  Binding of an HIV Rev peptide to Rev responsive element RNA induces formation of purine-purine base pairs.

Authors:  J L Battiste; R Tan; A D Frankel; J R Williamson
Journal:  Biochemistry       Date:  1994-03-15       Impact factor: 3.162

6.  Proflavine acts as a Rev inhibitor by targeting the high-affinity Rev binding site of the Rev responsive element of HIV-1.

Authors:  Eric S DeJong; Chia-en Chang; Michael K Gilson; John P Marino
Journal:  Biochemistry       Date:  2003-07-08       Impact factor: 3.162

7.  A molecular rheostat. Co-operative rev binding to stem I of the rev-response element modulates human immunodeficiency virus type-1 late gene expression.

Authors:  D A Mann; I Mikaélian; R W Zemmel; S M Green; A D Lowe; T Kimura; M Singh; P J Butler; M J Gait; J Karn
Journal:  J Mol Biol       Date:  1994-08-12       Impact factor: 5.469

8.  Structural mimicry of retroviral tat proteins by constrained beta-hairpin peptidomimetics: ligands with high affinity and selectivity for viral TAR RNA regulatory elements.

Authors:  Zafiria Athanassiou; Ricardo L A Dias; Kerstin Moehle; Neil Dobson; Gabriele Varani; John A Robinson
Journal:  J Am Chem Soc       Date:  2004-06-09       Impact factor: 15.419

9.  Small molecule modulators of HIV Rev/Rev response element interaction identified by random screening.

Authors:  Richard L Chapman; Thomas B Stanley; Richard Hazen; Edward P Garvey
Journal:  Antiviral Res       Date:  2002-06       Impact factor: 5.970

10.  Specific binding of a basic peptide from HIV-1 Rev.

Authors:  J Kjems; B J Calnan; A D Frankel; P A Sharp
Journal:  EMBO J       Date:  1992-03       Impact factor: 11.598
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  14 in total

1.  Design of RNA-targeting macrocyclic peptides.

Authors:  Matthew J Walker; Gabriele Varani
Journal:  Methods Enzymol       Date:  2019-06-13       Impact factor: 1.600

2.  Measuring cooperative Rev protein-protein interactions on Rev responsive RNA by fluorescence resonance energy transfer.

Authors:  Thomas Vercruysse; Sonalika Pawar; Wim De Borggraeve; Els Pardon; George N Pavlakis; Christophe Pannecouque; Jan Steyaert; Jan Balzarini; Dirk Daelemans
Journal:  RNA Biol       Date:  2011-03-01       Impact factor: 4.652

Review 3.  Approaches to Validate and Manipulate RNA Targets with Small Molecules in Cells.

Authors:  Jessica L Childs-Disney; Matthew D Disney
Journal:  Annu Rev Pharmacol Toxicol       Date:  2015-10-22       Impact factor: 13.820

4.  γ-AApeptides bind to RNA by mimicking RNA-binding proteins.

Authors:  Youhong Niu; Alisha Jonesy Jones; Haifan Wu; Gabriele Varani; Jianfeng Cai
Journal:  Org Biomol Chem       Date:  2011-08-08       Impact factor: 3.876

5.  A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.

Authors:  Matthew D Shortridge; Matthew J Walker; Tom Pavelitz; Yu Chen; Wen Yang; Gabriele Varani
Journal:  ACS Chem Biol       Date:  2017-05-02       Impact factor: 5.100

6.  Two-dimensional combinatorial screening identifies specific 6'-acylated kanamycin A- and 6'-acylated neamine-RNA hairpin interactions.

Authors:  Olga Aminova; Dustin J Paul; Jessica L Childs-Disney; Matthew D Disney
Journal:  Biochemistry       Date:  2008-12-02       Impact factor: 3.162

7.  Positional effects of click cyclization on β-hairpin structure, stability, and function.

Authors:  Jessica H Park; Marcey L Waters
Journal:  Org Biomol Chem       Date:  2013-01-07       Impact factor: 3.876

8.  Multivalent binding oligomers inhibit HIV Tat-TAR interaction critical for viral replication.

Authors:  Deyun Wang; Jaclyn Iera; Heather Baker; Priscilla Hogan; Roger Ptak; Lu Yang; Tracy Hartman; Robert W Buckheit; Alexandre Desjardins; Ao Yang; Pascale Legault; Venkat Yedavalli; Kuan-Teh Jeang; Daniel H Appella
Journal:  Bioorg Med Chem Lett       Date:  2009-10-23       Impact factor: 2.823

9.  Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein.

Authors:  Amy Davidson; Krystyna Patora-Komisarska; John A Robinson; Gabriele Varani
Journal:  Nucleic Acids Res       Date:  2010-08-19       Impact factor: 16.971

10.  An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb.

Authors:  Matthew D Shortridge; Paul T Wille; Alisha N Jones; Amy Davidson; Jasmina Bogdanovic; Eric Arts; Jonathan Karn; John A Robinson; Gabriele Varani
Journal:  Nucleic Acids Res       Date:  2019-02-20       Impact factor: 16.971
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