PURPOSE: To report a case of a dendritic epithelial defect with interface inflammation associated with Alternaria sp. after laser in situ keratomileusis (LASIK) surgery. METHODS: A case report of a 46-year-old woman who presented with a dendritic epithelial defect and interface inflammation after LASIK surgery. RESULTS: After an apparent post-LASIK herpes simplex keratitis with related interface inflammation failed to respond to medical therapy, cornea culture results were positive for Alternaria fungal sp. 2 weeks and 6 days after presentation. Viral cultures and polymerase chain reaction were negative for herpes simplex virus. Six months after penetrating keratoplasty (and 1 year after LASIK), the patient underwent a cataract extraction OD. Best-corrected visual acuity 18 months after the original LASIK procedure was 20/25 OD. CONCLUSIONS: Alternaria keratitis may present with a dendritic epithelial defect with interface inflammation mimicking herpes simplex virus.
PURPOSE: To report a case of a dendritic epithelial defect with interface inflammation associated with Alternaria sp. after laser in situ keratomileusis (LASIK) surgery. METHODS: A case report of a 46-year-old woman who presented with a dendritic epithelial defect and interface inflammation after LASIK surgery. RESULTS: After an apparent post-LASIK herpes simplex keratitis with related interface inflammation failed to respond to medical therapy, cornea culture results were positive for Alternariafungal sp. 2 weeks and 6 days after presentation. Viral cultures and polymerase chain reaction were negative for herpes simplex virus. Six months after penetrating keratoplasty (and 1 year after LASIK), the patient underwent a cataract extraction OD. Best-corrected visual acuity 18 months after the original LASIK procedure was 20/25 OD. CONCLUSIONS:Alternaria keratitis may present with a dendritic epithelial defect with interface inflammation mimicking herpes simplex virus.
Authors: Ching-Hsi Hsiao; Lung-Kun Yeh; Hung-Chi Chen; Hsin-Chiung Lin; Phil Y F Chen; David H K Ma; Hsin-Yuan Tan Journal: J Ophthalmol Date: 2014-03-20 Impact factor: 1.909