Literature DB >> 17893213

Serial whole-brain N-acetylaspartate concentration in healthy young adults.

D J Rigotti1, M Inglese, J S Babb, M Rovaris, B Benedetti, M Filippi, R I Grossman, O Gonen.   

Abstract

Although the concentration of N-acetylaspartate (NAA) is often used as a neuronal integrity marker, its normal temporal variations are not well documented. To assess them over the 1-2 year periods of typical clinical trials, the whole-brain NAA concentration was measured longitudinally, over 4 years, in a cohort of healthy young adults. No significant change (adjusted for both sex and age) was measured either interpersonally or intrapersonally over the entire duration of the study.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17893213      PMCID： PMC8134197          DOI： 10.3174/ajnr.A0712

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN： 0195-6108            Impact factor:   3.825


  14 in total

Review 1.  Magnetic resonance spectroscopy of the human brain.

Authors:  B Ross; S Bluml
Journal:  Anat Rec       Date:  2001-04

2.  N-acetylaspartate: usefulness as an indicator of viable neuronal tissue.

Authors:  D L Arnold; N de Stefano; P M Matthews; B D Trapp
Journal:  Ann Neurol       Date:  2001-12       Impact factor: 10.422

3.  Hippocampal formation glucose metabolism and volume losses in MCI and AD.

Authors:  S De Santi; M J de Leon; H Rusinek; A Convit; C Y Tarshish; A Roche; W H Tsui; E Kandil; M Boppana; K Daisley; G J Wang; D Schlyer; J Fowler
Journal:  Neurobiol Aging       Date:  2001 Jul-Aug       Impact factor: 4.673

Review 4.  The role of magnetic resonance techniques in understanding and managing multiple sclerosis.

Authors:  D H Miller; R I Grossman; S C Reingold; H F McFarland
Journal:  Brain       Date:  1998-01       Impact factor: 13.501

5.  Reproducibility of 1H-MRS in vivo.

Authors:  W M Brooks; S D Friedman; C A Stidley
Journal:  Magn Reson Med       Date:  1999-01       Impact factor: 4.668

6.  Total brain N-acetylaspartate concentration in normal, age-grouped females: quantitation with non-echo proton NMR spectroscopy.

Authors:  O Gonen; A K Viswanathan; I Catalaa; J Babb; J Udupa; R I Grossman
Journal:  Magn Reson Med       Date:  1998-11       Impact factor: 4.668

7.  Immunohistochemical localization of N-acetylaspartate in rat brain.

Authors:  J R Moffett; M A Namboodiri; C B Cangro; J H Neale
Journal:  Neuroreport       Date:  1991-03       Impact factor: 1.837

8.  Indirect evidence for early widespread gray matter involvement in relapsing-remitting multiple sclerosis.

Authors:  Matilde Inglese; Yulin Ge; Massimo Filippi; Andrea Falini; Robert I Grossman; Oded Gonen
Journal:  Neuroimage       Date:  2004-04       Impact factor: 6.556

Review 9.  Role of magnetic resonance imaging in the diagnosis and monitoring of multiple sclerosis: consensus report of the White Matter Study Group.

Authors:  M Filippi; V Dousset; H F McFarland; D H Miller; R I Grossman
Journal:  J Magn Reson Imaging       Date:  2002-05       Impact factor: 4.813

10.  A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging.

Authors:  Rachael I Scahill; Chris Frost; Rhian Jenkins; Jennifer L Whitwell; Martin N Rossor; Nick C Fox
Journal:  Arch Neurol       Date:  2003-07
View more
  10 in total

1.  Longitudinal whole-brain N-acetylaspartate concentration in healthy adults.

Authors:  D J Rigotti; I I Kirov; B Djavadi; N Perry; J S Babb; O Gonen
Journal:  AJNR Am J Neuroradiol       Date:  2011-04-21       Impact factor: 3.825

2.  Whole brain N-acetylaspartate concentration is conserved throughout normal aging.

Authors:  William E Wu; Achim Gass; Lidia Glodzik; James S Babb; Jochen Hirsch; Marc Sollberger; Lutz Achtnichts; Michael Amann; Andreas U Monsch; Oded Gonen
Journal:  Neurobiol Aging       Date:  2012-01-14       Impact factor: 4.673

3.  Two-year serial whole-brain N-acetyl-L-aspartate in patients with relapsing-remitting multiple sclerosis.

Authors:  D J Rigotti; M Inglese; I I Kirov; E Gorynski; N N Perry; J S Babb; J Herbert; R I Grossman; O Gonen
Journal:  Neurology       Date:  2012-04-18       Impact factor: 9.910

Review 4.  Consensus statement for diagnosis of subcortical small vessel disease.

Authors:  Gary A Rosenberg; Anders Wallin; Joanna M Wardlaw; Hugh S Markus; Joan Montaner; Leslie Wolfson; Costantino Iadecola; Berislav V Zlokovic; Anne Joutel; Martin Dichgans; Marco Duering; Reinhold Schmidt; Amos D Korczyn; Lea T Grinberg; Helena C Chui; Vladimir Hachinski
Journal:  J Cereb Blood Flow Metab       Date:  2016-01       Impact factor: 6.200

Review 5.  Whole-brain N-acetylaspartate as a surrogate marker of neuronal damage in diffuse neurologic disorders.

Authors:  D J Rigotti; M Inglese; O Gonen
Journal:  AJNR Am J Neuroradiol       Date:  2007-10-05       Impact factor: 3.825

6.  The whole-brain N-acetylaspartate correlates with education in normal adults.

Authors:  Lidia Glodzik; William E Wu; James S Babb; Lutz Achtnichts; Michael Amann; Marc Sollberger; Andreas U Monsch; Achim Gass; Oded Gonen
Journal:  Psychiatry Res       Date:  2012-10-30       Impact factor: 3.222

7.  Automated whole-brain N-acetylaspartate proton MRS quantification.

Authors:  Brian J Soher; William E Wu; Assaf Tal; Pippa Storey; Ke Zhang; James S Babb; Ivan I Kirov; Yvonne W Lui; Oded Gonen
Journal:  NMR Biomed       Date:  2014-09-05       Impact factor: 4.044

8.  Whole-brain N-acetylaspartate MR spectroscopic quantification: performance comparison of metabolite versus lipid nulling.

Authors:  J-B Hövener; D J Rigotti; M Amann; S Liu; J S Babb; P Bachert; A Gass; R I Grossman; O Gonen
Journal:  AJNR Am J Neuroradiol       Date:  2008-06-12       Impact factor: 3.825

9.  Serial Cerebral Metabolic Changes in Patients With Ischemic Stroke Treated With Autologous Bone Marrow Derived Mononuclear Cells.

Authors:  Muhammad E Haque; Refaat E Gabr; Sarah D George; Seth B Boren; Farhaan S Vahidy; Xu Zhang; Octavio D Arevalo; Susan Alderman; Ponnada A Narayana; Khader M Hasan; Elliott R Friedman; Clark W Sitton; Sean I Savitz
Journal:  Front Neurol       Date:  2019-02-25       Impact factor: 4.003

10.  N-acetylaspartate (NAA) induces neuronal differentiation of SH-SY5Y neuroblastoma cell line and sensitizes it to chemotherapeutic agents.

Authors:  Carmela Mazzoccoli; Vitalba Ruggieri; Tiziana Tataranni; Francesca Agriesti; Ilaria Laurenzana; Angelo Fratello; Nazzareno Capitanio; Claudia Piccoli
Journal:  Oncotarget       Date:  2016-05-03
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.