Mamdoh A Eskandar1. 1. Department of Obstetrics and Gynecology and Reproductive Medicine, King Khalid University, College of Medicine, Abha, Saudi Arabia. maeskandar@kku.edu.sa
Abstract
OBJECTIVE: The purpose of the present study was to determine if the use of a gonadotropin-releasing hormone (GnRH) agonist can improve pregnancy and live-birth rates during superovulation and intrauterine insemination (IUI). SUBJECTS AND METHODS: In this prospective study, which started in January 2004 and finished in October 2006, women aged 18-39 years underwent 500 cycles of superovulation/IUI with (n = 254) and without (n = 246) GnRH agonist. SETTING: Saudi Center for Assisted Reproduction, Abha, Saudi Arabia. RESULTS: There were no significant differences with regard to patient demographics between the studied groups. In addition, there was no statistically significant difference in the live-birth, ongoing and clinical pregnancy rates per cycle for patients who received GnRH agonist and patients who did not receive GnRH agonist. CONCLUSION: Superovulation/IUI cycles using GnRH agonist produce similar pregnancy rates to superovulation/IUI cycles without using GnRH agonist.
OBJECTIVE: The purpose of the present study was to determine if the use of a gonadotropin-releasing hormone (GnRH) agonist can improve pregnancy and live-birth rates during superovulation and intrauterine insemination (IUI). SUBJECTS AND METHODS: In this prospective study, which started in January 2004 and finished in October 2006, women aged 18-39 years underwent 500 cycles of superovulation/IUI with (n = 254) and without (n = 246) GnRH agonist. SETTING: Saudi Center for Assisted Reproduction, Abha, Saudi Arabia. RESULTS: There were no significant differences with regard to patient demographics between the studied groups. In addition, there was no statistically significant difference in the live-birth, ongoing and clinical pregnancy rates per cycle for patients who received GnRH agonist and patients who did not receive GnRH agonist. CONCLUSION: Superovulation/IUI cycles using GnRH agonist produce similar pregnancy rates to superovulation/IUI cycles without using GnRH agonist.